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Predictive risk factors for complicated pneumonia in Malaysian children
Jian Min Ooi1, Kah Peng Eg2,3, Karuthan Chinna4
1Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Insights
Complicated community-acquired pneumonia (CAPc) in Malaysian children is linked to Chinese ethnicity, less breastfeeding, no outpatient antibiotics, and parental smoking. These factors can help reduce CAPc burden.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Complicated community-acquired pneumonia (CAPc), including pleural effusion and empyema, is increasing in Southeast Asian children.
- The underlying reasons for this rise in CAPc are not well understood.
Purpose of the Study:
- To identify baseline characteristics associated with CAPc in Malaysian children.
- To explore risk factors and clinical parameters linked to CAPc development.
Main Methods:
- Retrospective study of children aged 2-16 years admitted with community-acquired pneumonia.
- Data collected from University Malaya Medical Centre between 2012 and 2014.
Main Results:
- Out of 343 children, 58 (17%) developed CAPc.
- Risk factors identified: Chinese ethnicity, reduced breastfeeding, no outpatient antibiotics, parental smoking.
- Clinical indicators: increased respiratory rate and thrombocytosis.
Conclusions:
- Identified modifiable risk factors for CAPc in Malaysian children.
- Findings can inform strategies to decrease the incidence and severity of pneumonia complications.
Aim:
To investigate baseline characteristics associated with complicated community-acquired pneumonia (CAPc) in Malaysian children. CAPc, such as pleural effusion and/or empyema, is on the rise, especially in Southeast Asian children, and the reasons for this are unknown.
Methods:
A retrospective study was conducted on all children aged 2-16 years who were admitted to the University Malaya Medical Centre with community-acquired pneumonia between 2012 and 2014.
Results:
In this study, of the 343 children, 58 (17%) developed CAPc. Chinese ethnicity (P < 0.001), reduced breastfeeding duration (P = 0.003), not receiving outpatient antibiotic (P < 0.001) and exposure to parental smoking (P < 0.001) were identified as risk factors for CAPc. Markedly increased respiratory rate (P = 0.021) and thrombocytosis (P < 0.001) were noted as the clinical parameters for CAPc.
Conclusion:
This study identifies some modifiable risk to reduce the burden of pneumonia complications.
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