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Updated: Feb 5, 2026

One-channel Cell-attached Patch-clamp Recording
Published on: June 9, 2014
Positive reactions to gold sodium thiosulfate in patch test panels (TRUE Test) in Japan: A multicentre study
Kayoko Suzuki1, Akiko Yagami1, Akiko Ito2,3
1Department of Allergology, Fujita Health University Second Educational Hospital, Aichi, Japan.
Background:
The proportion of positive test results with gold sodium thiosulfate included in a patch test panel (P-GST) had been found to be greater than that with gold sodium thiosulfate 0.5% pet. by allergEAZE (A-GST).
Objectives:
To compare positive reactions to P-GST and A-GST, and to evaluate late reactions after the day (D) 7 reading.
Methods:
A retrospective analysis was performed of 588 patients at participating departments (119 males; 469 females) who were patch tested with P-GST and A-GST in May 2015 to March 2016.
Results:
Positive test reactions to P-GST and A-GST were observed in 15% and 6% of patients, respectively. Three patients reported a positive reaction occurring after the D7 reading.
Conclusions:
Gold sodium thiosulfate often gives a positive reaction after 2 to 3 weeks, and, in such cases, the positive reaction may be sustained, so it is recommended to assess the reaction for up to 1 month after application.
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