Related Experiment Video

Updated: Feb 5, 2026

Intravital Microscopy of Leukocyte-endothelial and Platelet-leukocyte Interactions in Mesenterial Veins in Mice
05:12

Intravital Microscopy of Leukocyte-endothelial and Platelet-leukocyte Interactions in Mesenterial Veins in Mice

Published on: August 13, 2015

13.0K

[NOTHROMBEL EFFECT ON THE FORMATION OF PLATELET-LEUKOCYTE COMPLEXES INDUCED BY THROMBIN]

O S Veselkina, N N Petrishchev, L V Vasina

    Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova
    |September 11, 2018
    PubMed
    Summary

    Nothrombel effectively inhibits platelet-leukocyte complex formation, showing greater potency than Aspirin. This compound offers a promising new avenue for managing conditions related to platelet aggregation and inflammation.

    More Related Videos

    Characterization of Leukocyte-platelet Rich Fibrin, A Novel Biomaterial08:14

    Characterization of Leukocyte-platelet Rich Fibrin, A Novel Biomaterial

    Published on: September 29, 2015

    13.5K
    Bioenergetics and the Oxidative Burst: Protocols for the Isolation and Evaluation of Human Leukocytes and Platelets11:40

    Bioenergetics and the Oxidative Burst: Protocols for the Isolation and Evaluation of Human Leukocytes and Platelets

    Published on: March 27, 2014

    38.3K

    Related Concept Videos

    Formation of Complex Ions03:45

    Formation of Complex Ions

    A type of Lewis acid-base chemistry involves the formation of a complex ion (or a coordination complex) comprising a central atom, typically a transition metal cation, surrounded by ions or molecules called ligands. These ligands can be neutral molecules like H2O or NH3, or ions such as CN− or OH−. Often, the ligands act as Lewis bases, donating a pair of electrons to the central atom. These types of Lewis acid-base reactions are examples of a broad subdiscipline called coordination...
    26.2K
    Formation of the Platelet Plug01:22

    Formation of the Platelet Plug

    The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
    As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...
    9.3K
    Disorders of Leukocytes01:27

    Disorders of Leukocytes

    Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
    Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...
    2.0K
    Classification of Leukocytes01:30

    Classification of Leukocytes

    Leukocytes are classified into two groups based on the presence or absence of cytoplasmic granules. Granular leukocytes, which contain granules, belong to the myeloid lineage and are divided into three subtypes: neutrophils, eosinophils, and basophils. These cells are roughly spherical and characterized by the granules in their cytoplasm.
    Neutrophils are the most abundant type of granular leukocytes, comprising 50-70% of all leukocytes. They feature small, evenly distributed granules and a...
    5.9K
    Structure and Function of Leukocytes01:21

    Structure and Function of Leukocytes

    An adult in good health typically has between 4,500 and 11,000 leukocytes, or white blood cells, per microliter of blood, which constitutes about 1% of the total blood volume. Unlike red blood cells, white blood cells contain a nucleus and other cellular organelles but do not have hemoglobin. Most white blood cells reside in connective tissues, particularly in lymphatic organs such as the lymph nodes, with only a small fraction present in circulating blood.
    White blood cells protect the body...
    4.4K
    Structure and Function of Platelets01:18

    Structure and Function of Platelets

    The cell fragments known as platelets are disc-shaped, with an average diameter of about 3 μm and a thickness of roughly 1 μm. They play a crucial role in the body's vascular clotting system, which also involves plasma proteins, blood cells, and blood vessel tissues.
    Platelets are continually replenished, circulating in the bloodstream for 9-12 days before being removed by phagocytes, primarily in the spleen. A microliter of circulating blood contains between 150,000 and 450,000...
    3.6K