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Related Experiment Video

Updated: Feb 5, 2026

Monitoring Spatial Segregation in Surface Colonizing Microbial Populations

Monitoring Spatial Segregation in Surface Colonizing Microbial Populations

Published on: October 29, 2016

Combining human STR and microbial population profiling: Two case reports.

Frederike C A Quaak¹, Yvonne van de Wal¹, Petra A Maaskant-van Wijk¹

¹Netherlands Forensic Institute, P.O. Box 24044, 2490 AA, The Hague, The Netherlands.

Forensic Science International. Genetics

|September 11, 2018

Summary

Forensic science advances with cell type identification in human traces. Microbial profiling aids activity level analysis, complementing DNA profiling for comprehensive case evaluation.

Keywords:

Case report Human cell type identification Microbial population profiling

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Area of Science:

Forensic Science
Microbiology
Genetics

Background:

Cell type identification is crucial in forensic investigations for determining the origin and deposition of human traces.
Evaluating 'beyond-the-source' or activity level information requires understanding the cellular source of DNA profiles.
Traditional human STR profiling addresses the sub-source (donor) question.

Observation:

Two criminal cases utilized both human STR profiling and microbial population profiling on the same trace samples.
Human STR profiling was employed to address the sub-source identification.
Microbial population profiling was used to investigate the source of the trace, providing activity-level insights.

Findings:

Combined human and microbial profiling offers a dual approach to forensic trace analysis.
Microbial profiling can provide complementary information to human DNA analysis, aiding in activity-level assessments.
The Bayesian framework was successfully applied to evaluate the combined evidence from both profiling methods.

Implications:

This integrated approach enhances the evaluative power of forensic evidence in criminal investigations.
Microbial population profiling represents a valuable tool for inferring activities related to trace deposition.
Future forensic casework can benefit from the synergistic application of human and microbial DNA analysis for a more complete understanding of events.