Related Experiment Video
Updated: Feb 5, 2026

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
Published on: August 18, 2020
Whack induced psychosis: A case series.
Emam El-Higaya1, Mohamed Ahmed2, Brian Hallahan3
1Department of Psychiatry,University College Hospital,Galway,Ireland.
A new psychoactive substance, Whack, containing 4-fluorotropacocaine and desoxypipradrol, was linked to acute psychotic states in two individuals. Both patients responded well to atypical antipsychotic treatment.
Area of Science:
- Toxicology
- Psychiatry
- Pharmacology
Background:
- Emerging novel psychoactive substances (NPS) pose challenges to public health.
- Head shops have historically distributed substances like Whack.
- The constituents of Whack include 4-fluorotropacocaine and desoxypipradrol.
Purpose of the Study:
- To report on the clinical effects of the novel psychoactive substance Whack.
- To describe the psychiatric outcomes and treatment response in individuals using Whack.
Main Methods:
- Case series presentation of two individuals with acute psychotic states.
- Clinical assessment of psychiatric and affective symptoms.
- Monitoring of treatment response to atypical antipsychotics.
Main Results:
- Both subjects developed acute psychotic states with affective and anxiety symptoms after Whack use.
- Inpatient treatment was required for both cases.
- A good treatment response was observed with atypical antipsychotic agents.
Conclusions:
- Whack, containing 4-fluorotropacocaine and desoxypipradrol, can induce acute psychotic states.
- Atypical antipsychotics appear effective in managing Whack-induced psychosis.
- This is the first published case series on the psychoactive substance Whack.
More Related Videos
07:31Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
Published on: May 15, 2020
05:52Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
Related Concept Videos
Psychosis: Goals of Pharmacotherapy
Psychosis and Antipsychotic Drugs: Overview
Resistors In Series
In a series circuit, the...
Series Resonance
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
Series and Parallel Capacitors
First, consider capacitors connected in series to a battery. In this configuration, the plate connected to the battery's positive terminal develops a positive charge, while the plate attached to the negative terminal becomes negatively charged. An equal magnitude of charge is induced on the...