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The Enhanced Interactive Physical and Cognitive Exercise System (iPACES

Kathryn Wall1,2, Jessica Stark3, Alexa Schillaci4

  • 1Healthy Aging & Neuropsychology Lab, Union College, Schenectady, NY 12308, USA. wallk@union.edu.

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|September 12, 2018
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Summary
This summary is machine-generated.

An in-home neuro-exergame improved executive function in older adults with mild cognitive impairment. This technology may help combat cognitive decline and dementia.

Keywords:
Alzheimer’sIGF-1cortisoldementiaexecutive functionexerciseexergamemild cognitive impairmentneurocognitive disorderolder adult

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Area of Science:

  • Gerontology
  • Neuroscience
  • Cognitive Psychology

Background:

  • Global longevity increases demand for interventions against cognitive decline in older adults.
  • Mild cognitive impairment (MCI), now mild neurocognitive disorder (mNCD), is a target for cognitive enhancement strategies.
  • Previous research explored interactive physical and cognitive exercise, necessitating improved usability and mechanism exploration.

Purpose of the Study:

  • To assess the cognitive benefits of an updated, user-friendly in-home neuro-exergame (iPACES™ v2.0).
  • To explore potential neurobiological mechanisms underlying cognitive improvements.
  • To replicate and extend prior findings on cognitive exercise interventions.

Main Methods:

  • A quasi-experimental, within-subjects pilot trial involving older adults with mNCD.
  • A three-month in-home intervention using a portable neuro-exergame (iPACES™ v2.0) with a virtual reality cycling component (Memory Lane™).
  • Neuropsychological assessments at baseline and post-intervention, with analysis of salivary biomarkers (cortisol, IGF-1).

Main Results:

  • Significant improvement in executive function, specifically the Stroop test (d = 0.68, p = 0.02).
  • No other significant cognitive improvements were noted.
  • Salivary biomarker changes (cortisol, IGF-1) showed significant associations with cognitive improvements.

Conclusions:

  • A portable, in-home neuro-exergame shows promise as a practical tool to support cognitive function in older adults.
  • The findings suggest potential neurobiological underpinnings for the observed cognitive benefits.
  • Further research is warranted to validate these pilot results and explore broader applications.