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Related Concept Videos

Biofilms01:29

Biofilms

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Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
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Oral Cavity01:11

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The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
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Oral Hypoglycemic Agents: Glinides01:06

Oral Hypoglycemic Agents: Glinides

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Repaglinide (Prandin) and Nateglinide (Starlix), known as glinides, are oral insulin secretagogues that stimulate insulin release from pancreatic β cells by closing the ATP-sensitive potassium channels (KATP channel). Repaglinide controls insulin release from pancreatic β cells by managing potassium efflux. It shares two binding sites with sulfonylureas and also has a unique site, indicating overlapping mechanisms of action. With a rapid onset and a 4-7 hour duration, it effectively...
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Psychosexual Stages of Personality: Oral01:16

Psychosexual Stages of Personality: Oral

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The oral stage is the initial phase of Sigmund Freud's theory of psychosexual development, occurring from birth to approximately 12 to 18 months. During this period, the infant's mouth serves as the primary source of pleasure, with actions such as sucking, chewing, biting, and drinking playing a crucial role in reducing tension. These activities are essential not only for nourishment but also for the infant's psychological and emotional satisfaction.
Weaning, typically occurring...
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Assessing Body Temperature - Oral01:14

Assessing Body Temperature - Oral

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Here are the steps to accurately measure oral temperature using an electronic thermometer:
Step 1:
Start by practicing proper hand hygiene to prevent the spread of microorganisms.
Step 2:
Take the thermometer out of the charging unit, switch it on, and wait for the ready sign.
Step 3:
Gently slide the probe cover until a click is heard. This simple action prevents cross-contamination and ensures the correct placement of the probe cover.
Step 4:
Instruct the patient to open their mouth and place...
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Oral Hypoglycemic Agents: Sulfonylureas01:17

Oral Hypoglycemic Agents: Sulfonylureas

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Sulfonylureas are oral hypoglycemic agents utilized in treating type 2 diabetes. They are characterized by their unique sulfonylurea chemical structure. The family of sulfonylureas is divided into generations. First-generation sulfonylureas, including tolbutamide (Orinase), chlorpropamide (Diabinese), and tolazamide (Tolinase), trigger insulin release from pancreatic β cells and enhance peripheral tissues' insulin sensitivity. The second-generation members, such as glipizide...
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Related Experiment Video

Updated: Feb 5, 2026

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
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Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

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Oral Biofilms: Development, Control, and Analysis.

Daniela Berger1, Aviva Rakhamimova2, Andrew Pollack3

  • 1Department of Pharmaceutical and Biomedical Sciences, Touro College of Pharmacy, New York, NY 10027, USA. dberger@student.touro.edu.

High-Throughput
|September 12, 2018
PubMed
Summary
This summary is machine-generated.

Controlling pathogenic oral biofilms, which resist conventional antimicrobials, is crucial. Emerging chemical, biological, and analytical methods offer new strategies for managing these challenging microbial communities.

Keywords:
antimicrobialbiofilmhigh-throughput analysis

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Area of Science:

  • Microbiology
  • Oral Health
  • Biotechnology

Background:

  • The oral cavity hosts numerous microbial species, forming biofilms that can cause infections and systemic diseases.
  • Pathogenic oral biofilms are difficult to eradicate with traditional antimicrobial agents.
  • Advances in science offer novel strategies for controlling and analyzing oral biofilms.

Purpose of the Study:

  • To provide an understanding of oral biofilm development.
  • To describe emerging methods for controlling oral biofilms.
  • To overview high-throughput analytical techniques for biofilm analysis.

Main Methods:

  • Literature review on biofilm development.
  • Analysis of current chemical and biological control strategies.
  • Exploration of advanced analytical techniques for biofilm characterization.

Main Results:

  • Oral biofilms present a significant challenge due to microbial complexity and resistance.
  • Novel chemical and biological agents show promise in combating pathogenic biofilms.
  • High-throughput methods enable detailed analysis of biofilm structure and function.

Conclusions:

  • Effective control of oral pathogenic biofilms requires innovative approaches beyond conventional antimicrobials.
  • Emerging technologies offer promising solutions for biofilm management and characterization.
  • Further research into these advanced methods is essential for improving oral health outcomes.