Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Characteristics and Nomenclature of Copolymers01:24

Characteristics and Nomenclature of Copolymers

3.3K
Copolymers are the products obtained from the polymerization of multiple monomer species. So, in a polymer chain itself, there can be multiple repeating units that come from different monomers. The process of synthesizing a polymer from different monomer species is called copolymerization. When two monomers are involved, the polymer is known as a bipolymer. Polymers with three and four monomers are termed terpolymers and quaterpolymers, respectively. Figure 1 depicts the copolymerization of...
3.3K
Base Quantities and Derived Quantities01:14

Base Quantities and Derived Quantities

26.3K
In any system of units, the units for some physical quantities must be specified through a measurement process. These measurements are the base quantities of the system, and their units are the base units of the system. The algebraic combinations of the base values can then be used to express all other physical quantities. Each of these physical quantities is then referred to as a derived quantity, with each unit being referred to as a derived unit.
The International Organization for...
26.3K
Measurement: Derived Units03:02

Measurement: Derived Units

55.7K
The International System of Units or SI system, by international agreement, has fixed measurement units for seven fundamental properties: length, mass, time, temperature, electric current, amount of substance, and luminosity. These are called the SI base units.
55.7K
Higher Derivatives01:29

Higher Derivatives

91
In calculus, higher-order derivatives extend the idea of differentiation beyond the first derivative to capture successive rates of change. These derivatives provide detailed information about the behavior of functions and have important applications in both mathematics and physics. To illustrate these concepts, consider the example functionwhich serves as a useful case study for exploring higher derivatives.The first derivative represents the slope of the original function. The second...
91
Derivatives01:15

Derivatives

153
DerivativesThe concept of instantaneous rate of change is fundamental in both mathematics and physics, particularly in describing how a moving object alters its position with respect to time. This rate is captured mathematically through the derivative of a function. The derivative at a point represents the slope of the tangent line to the curve of the function at that point and quantifies how the function’s output changes per infinitesimal change in input.Derivative of the Square Root...
153
The Derivative as a Function01:26

The Derivative as a Function

105
A derivative quantifies how a function changes in response to variations in its input. It provides a localized rate of change, representing the slope of the tangent line to the function at any given point. When this process is applied systematically across the entire domain of the function, it yields a new function—the derivative function—which encodes the rate of change at every point. This concept is central to calculus and essential for understanding the behavior of dynamic...
105

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Synthesis and Optoelectronic Properties of Branched Polystyrene-<i>graft</i>-Polyfluorene Copolymers.

Micromachines·2026
Same author

A magnetic resonance imaging-guided drug delivery system for premetastatic niche theranostics and colorectal cancer liver metastasis intervention.

Journal of nanobiotechnology·2026
Same author

Correction: Tumor-triggered personalized microRNA cocktail therapy for hepatocellular carcinoma.

Biomaterials science·2026
Same author

Correction: Metabolically engineered bacteria as light-controlled living therapeutics for anti-angiogenesis tumor therapy.

Materials horizons·2026
Same author

Star-Shaped Polyphenolic Polypeptides Serving as Assembling-Typed Drug Carriers.

Biomacromolecules·2026
Same author

Amine-Functionalized NiCoFe<sub>2</sub>O<sub>4</sub> Nanoparticle-Embedded Sodium Alginate/Polyvinyl Alcohol Hydrogel Beads as a ROS-Generating, pH-Responsive Drug Carrier.

International journal of nanomedicine·2026

Related Experiment Video

Updated: Feb 5, 2026

Author Spotlight: Development and Challenges of Feeding Assays for Insect Pest Management
04:51

Author Spotlight: Development and Challenges of Feeding Assays for Insect Pest Management

Published on: May 26, 2023

1.8K

A Phytochemical-Based Copolymer Derived from

Wing-Fu Lai1,2, Marie C Lin3, Guping Tang4

  • 1Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China. wflai@szu.edu.cn.

Molecules (Basel, Switzerland)
|September 12, 2018
PubMed
Summary
This summary is machine-generated.

Coriolus versicolor polysaccharopeptides (PSP) were conjugated with poly(ethylenimine) (PEI) to create a novel gene carrier. This PSP-PEI copolymer demonstrated significantly enhanced gene transfer efficiency for potential cancer therapies.

Keywords:
Coriolus versicolorgene deliveryherbspoly(ethylenimine)polysaccharopeptide

More Related Videos

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

8.2K
Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by &#960;-&#960; Stacking Interactions
10:53

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions

Published on: October 10, 2016

14.6K

Related Experiment Videos

Last Updated: Feb 5, 2026

Author Spotlight: Development and Challenges of Feeding Assays for Insect Pest Management
04:51

Author Spotlight: Development and Challenges of Feeding Assays for Insect Pest Management

Published on: May 26, 2023

1.8K
Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

8.2K
Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by &#960;-&#960; Stacking Interactions
10:53

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions

Published on: October 10, 2016

14.6K

Area of Science:

  • Biomedical Engineering
  • Pharmacology
  • Traditional Chinese Medicine

Background:

  • Coriolus versicolor, a traditional Chinese medicine, contains active polysaccharopeptides (PSP) used in cancer adjuvant therapy.
  • Developing efficient gene delivery vectors is crucial for cancer treatment.
  • Phytochemicals offer a potential source for novel biomaterials in gene therapy.

Purpose of the Study:

  • To conjugate Coriolus versicolor PSP with poly(ethylenimine) (PEI) to create a novel gene vector.
  • To evaluate the physicochemical properties and gene transfer efficiency of the resulting PSP-PEI copolymer.
  • To explore the potential of traditional Chinese medicine-derived compounds in gene vector development.

Main Methods:

  • Conjugation of Coriolus versicolor PSP with PEI.
  • Assessment of pH buffering capacity and DNA compaction ability of PSP and PSP-PEI.
  • In vitro evaluation of gene transfection efficiency of PSP-PEI compared to PSP.

Main Results:

  • The PSP-PEI copolymer exhibited significantly increased pH buffering capacity and DNA compaction ability compared to PSP alone.
  • In vitro transfection efficiency of PSP-PEI was 10 to 20-fold higher than that of PSP.
  • This study presents a proof-of-concept for using bioactive phytochemicals as gene vectors.

Conclusions:

  • PSP-PEI copolymer represents a promising new gene carrier developed from a traditional Chinese medicine.
  • The enhanced gene transfer capabilities suggest potential applications in multi-therapeutic gene carriers for cancer treatment.
  • Bioactive herbal ingredients can be further explored for advanced gene vector development.