Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Standard Enthalpy of Formation02:37

Standard Enthalpy of Formation

49.3K
Enthalpy changes are typically tabulated for reactions in which both the reactants and products are at the same conditions. A standard state is a commonly accepted set of conditions used as a reference point for the determination of properties under other different conditions. For chemists, the IUPAC standard state refers to materials under a pressure of 1 bar and solutions at 1 M and does not specify a temperature. Many thermochemical tables list values with a standard state of 1 atm. Because...
49.3K
Standard Electrode Potentials03:02

Standard Electrode Potentials

50.4K
On comparing the reactivity of silver and lead, it is observed that the two ionic species, Ag+ (aq) and Pb2+ (aq), show a difference in their redox reactivity towards copper: the silver ion undergoes spontaneous reduction, while the lead ion does not. This relative redox activity can be easily quantified in electrochemical cells by a property called cell potential. This property is commonly known as cell voltage in electrochemistry, and it is a measure of the energy which accompanies the charge...
50.4K
Measurement: Standard Units03:38

Measurement: Standard Units

80.9K
Every measurement provides three kinds of information: the size or magnitude of the measurement (a number), a standard of comparison for the measurement (a unit), and an indication of the uncertainty of the measurement. While the number and unit are explicitly represented when a quantity is written, the uncertainty is an aspect of the errors in the measurement results.
80.9K
Calculating Standard Free Energy Changes02:49

Calculating Standard Free Energy Changes

25.6K
The free energy change for a reaction that occurs under the standard conditions of 1 bar pressure and at 298 K is called the standard free energy change. Since free energy is a state function, its value depends only on the conditions of the initial and final states of the system. A convenient and common approach to the calculation of free energy changes for physical and chemical reactions is by use of widely available compilations of standard state thermodynamic data. One method involves the...
25.6K
Standard Solutions01:14

Standard Solutions

2.5K
Standard solutions refer to solutions with a precisely known concentration or composition. A primary standard is a highly pure, high molar mass, stable substance that is entirely soluble in water, the most commonly used solvent in analytical chemistry. The primary standard solution can be used to standardize secondary standards, which are substances with known concentrations but are less pure and stable. Standard solutions are essential for achieving accurate and reliable results in analytical...
2.5K
Standard Precaution01:26

Standard Precaution

3.1K
Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
3.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The pathobiology of human fungal infections.

Nature reviews. Microbiology·2024
Same author

The Molecular Architecture and Mode of Action of <i>Clostridium perfringens</i> ε-Toxin.

Toxins·2024
Same author

Strep A: challenges, opportunities, vaccine-based solutions and economics.

NPJ vaccines·2024
Same author

Progress with COVID vaccine development and implementation.

NPJ vaccines·2024
Same author

Is <i>Clostridium perfringens</i> epsilon toxin associated with multiple sclerosis?

Multiple sclerosis (Houndmills, Basingstoke, England)·2023
Same author

Comparison of the impact of two key fungal signalling pathways on Zymoseptoria tritici infection reveals divergent contribution to invasive growth through distinct regulation of infection-associated genes.

Molecular plant pathology·2023

Related Experiment Video

Updated: Feb 5, 2026

Standardized Method for Measuring Collection Efficiency from Wipe-sampling of Trace Explosives
07:22

Standardized Method for Measuring Collection Efficiency from Wipe-sampling of Trace Explosives

Published on: April 10, 2017

9.9K

Standardization of

Olivia L Champion1, Richard W Titball2, Steven Bates3

  • 1Biosystems Technology Ltd., 1 Colleton Crescent, Exeter EX2 4DG, UK. o.champion@biosystemstechnology.com.

Journal of Fungi (Basel, Switzerland)
|September 12, 2018
PubMed
Summary
This summary is machine-generated.

Standardizing Galleria mellonella (wax moth) larvae infection models improves research. This review details best practices for larvae selection, dosing, and illness scoring in fungal infection studies.

Keywords:
Galleria mellonellaend pointfungigenomeinfection modelpathological score

More Related Videos

A Standardized Method for Measurement of Elbow Kinesthesia
07:56

A Standardized Method for Measurement of Elbow Kinesthesia

Published on: October 10, 2020

7.9K
Standardization of Basket Use in Sialendoscopy: A Ten-Year Retrospective Study
09:36

Standardization of Basket Use in Sialendoscopy: A Ten-Year Retrospective Study

Published on: June 6, 2025

584

Related Experiment Videos

Last Updated: Feb 5, 2026

Standardized Method for Measuring Collection Efficiency from Wipe-sampling of Trace Explosives
07:22

Standardized Method for Measuring Collection Efficiency from Wipe-sampling of Trace Explosives

Published on: April 10, 2017

9.9K
A Standardized Method for Measurement of Elbow Kinesthesia
07:56

A Standardized Method for Measurement of Elbow Kinesthesia

Published on: October 10, 2020

7.9K
Standardization of Basket Use in Sialendoscopy: A Ten-Year Retrospective Study
09:36

Standardization of Basket Use in Sialendoscopy: A Ten-Year Retrospective Study

Published on: June 6, 2025

584

Area of Science:

  • * Invertebrate immunology
  • * Infectious disease research
  • * Drug discovery

Background:

  • * Galleria mellonella (wax moth) larvae are a valuable non-mammalian model for studying infections.
  • * Current research is limited by inconsistent larval quality and non-standardized experimental protocols.
  • * Standardization is crucial to unlock the full potential of this model system.

Purpose of the Study:

  • * To review best practices for utilizing Galleria mellonella larvae in infection research.
  • * To provide guidance on selecting appropriate larvae, standardizing dosing, and scoring infection severity.
  • * To highlight the benefits of standardized protocols for high-throughput screening and antimicrobial development.

Main Methods:

  • * Literature review of existing protocols and best practices for Galleria mellonella infection models.
  • * Discussion of critical parameters including larval sourcing, storage, and handling.
  • * Analysis of methods for accurate pathogen inoculation and assessment of host response.

Main Results:

  • * Identified key variables affecting larval quality and experimental reproducibility.
  • * Outlined standardized protocols for larval infection, including pathogen dosing and route of administration.
  • * Presented validated methods for quantifying larval mortality and signs of infection.

Conclusions:

  • * Standardized protocols for Galleria mellonella infection models enhance experimental reliability and reproducibility.
  • * Adoption of these standards will facilitate high-throughput screening of microbial mutants and drug candidates.
  • * This approach accelerates the early-stage research and development of novel antimicrobials.