[Recent research progress of selenium polysaccharides from medicinal plants]

Area of Science:

• Biochemistry
• Pharmacology
• Medicinal Chemistry

Background:

• Selenium polysaccharides (Se-polysaccharides) are organic selenium compounds combining selenium and polysaccharide properties.
• They exhibit superior biological activities and bioavailability compared to individual components.
• These compounds are increasingly utilized in medical applications, including immunomodulation, anti-tumor, anti-oxidation, and anti-aging therapies.

Purpose of the Study:

• To systematically review the main sources and biological activities of Se-polysaccharides derived from medicinal plants.
• To provide a foundational understanding for future research into Se-polysaccharides.
• To highlight the growing research interest in Se-polysaccharides from medicinal plants due to their unique pharmacological properties.

Main Methods:

• Literature review of scientific publications on Se-polysaccharides from medicinal plants.
• Systematic introduction of identified sources and documented biological activities.
• Discussion of current limitations and future research directions.

Main Results:

• Se-polysaccharides demonstrate significant potential in various therapeutic areas.
• Medicinal plants are a key source for these bioactive compounds.
• Challenges remain in the separation, purification, and structural elucidation of Se-polysaccharides.

Conclusions:

• Se-polysaccharides represent a promising class of compounds with broad medical applications.
• Further investigation into their complex structures and in vivo mechanisms is crucial.
• This review establishes a basis for advancing Se-polysaccharide research and development.