Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Adhesion01:14

Adhesion

44.5K
Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules.
Capillary action is a result of water’s adhesive tendencies. When a narrow...
44.5K
Integration by Parts: Indefinite Integrals01:26

Integration by Parts: Indefinite Integrals

183
Integration by parts is a fundamental technique in calculus for evaluating integrals involving the product of two functions. It is particularly useful when direct integration is not feasible. The method is based on the product rule for differentiation, which states that the derivative of a product equals the derivative of the first function times the second, plus the first function times the derivative of the second. By integrating this identity and rearranging terms, the integration by parts...
183
Integration by Parts: Definite Integrals01:23

Integration by Parts: Definite Integrals

85
Definite integrals involving the product of two functions over a fixed interval can be evaluated using integration by parts. This method rewrites the integral as the difference of a product evaluated at the endpoints and a remaining definite integral that is often simpler to compute.A representative example is the definite integral of the inverse tangent function. Since there is no direct integration formula for arctan ⁡x, the integrand is rewritten as a product of arctan⁡ x and the...
85
Cell Adhesion in Plants01:14

Cell Adhesion in Plants

3.4K
Plants have rigid cell walls that are made up of cell wall polysaccharides that mediate cell-cell adhesion. The primary cell walls of plants consist of two independent and interacting polysaccharide networks: a pectin matrix that embeds the second network comprising cellulose and hemicelluloses.
Pectins are complex heteropolymers mainly composed of negatively-charged α-D-glucopyranosyl uronic acid and some neutral glycosyl residues such as α-L-rhamnopyranose, α-L-arabinofuranose,...
3.4K
Immunoglobulin-like Cell Adhesion Molecules01:31

Immunoglobulin-like Cell Adhesion Molecules

4.4K
Immunoglobulin-like cell adhesion molecules or Ig-CAMs are a versatile group of cell surface glycoproteins belonging to the immunoglobulin protein superfamily. Ig-CAMs possess the characteristic immunoglobulin protein domains and other domains such as the fibronectin type III domain. The Ig domains are glycosylated to varying degrees in different Ig-CAMs.
Ig-CAMs exhibit either homophilic binding (to other Ig-CAMs) or heterophilic binding (to other ligands such as integrins). While most Ig-CAMs...
4.4K
Intracellular Signaling Affects Focal Adhesions01:17

Intracellular Signaling Affects Focal Adhesions

3.6K
Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely integrated into the membrane structure. Their hydrophobic membrane-spanning regions interact with the phospholipid bilayer's hydrophobic region. These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors. They activate intracellular response cascades when their effectors are bound and active.
Some...
3.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unifying Environmental Stress Cracking and Mechano-Sorptive Creep Under the Umbrella of Mechano-Sorptive Phenomena.

Biomimetics (Basel, Switzerland)·2026
Same author

Incorporating Carbamate Functionalities in Multifunctional Monomer System Enhances Mechanical Properties of Methacrylate Dental Adhesives.

Polymers·2025
Same author

Genetic disease risks of under-represented founder populations in New York City.

PLoS genetics·2025
Same author

Editorial: Next-generation dental materials engineered for mineralized tissue reconstruction: advances, challenges and opportunities.

Frontiers in dental medicine·2025
Same author

Multistep Self-Assembly of the Gold-Binding Peptide AuBP1.

The journal of physical chemistry. B·2025
Same author

Probing Solid-Binding Peptide Self-Assembly Kinetics Using a Frequency Response Cooperativity Model.

Biomimetics (Basel, Switzerland)·2025

Related Experiment Video

Updated: Feb 5, 2026

Oral Biofilm Formation on Different Materials for Dental Implants
11:19

Oral Biofilm Formation on Different Materials for Dental Implants

Published on: June 24, 2018

12.2K

Modulating pH through lysine integrated dental adhesives.

Linyong Song1, Xueping Ge1, Qiang Ye1

  • 1Institute for Bioengineering Research, School of Engineering, University of Kansas, 1530 W. 15th Street, Lawrence, KS 66045-7609, USA.

Dental Materials : Official Publication of the Academy of Dental Materials
|September 12, 2018
PubMed
Summary

Adding lysine to dental adhesives enhances polymerization and neutralizes acidic environments, potentially improving composite restoration durability. This amino acid integration shows promise for future bioactive dental materials.

Keywords:
BufferingDental adhesiveHybrid layerLysineNeutralizationPhoto-polymerizationThermal degradation

More Related Videos

Accuracy in Dental Medicine, A New Way to Measure Trueness and Precision
07:57

Accuracy in Dental Medicine, A New Way to Measure Trueness and Precision

Published on: April 29, 2014

14.0K
Application of Light-cured Dental Adhesive Resin for Mounting Electrodes or Microdialysis Probes in Chronic Experiments
16:30

Application of Light-cured Dental Adhesive Resin for Mounting Electrodes or Microdialysis Probes in Chronic Experiments

Published on: July 30, 2007

15.8K

Related Experiment Videos

Last Updated: Feb 5, 2026

Oral Biofilm Formation on Different Materials for Dental Implants
11:19

Oral Biofilm Formation on Different Materials for Dental Implants

Published on: June 24, 2018

12.2K
Accuracy in Dental Medicine, A New Way to Measure Trueness and Precision
07:57

Accuracy in Dental Medicine, A New Way to Measure Trueness and Precision

Published on: April 29, 2014

14.0K
Application of Light-cured Dental Adhesive Resin for Mounting Electrodes or Microdialysis Probes in Chronic Experiments
16:30

Application of Light-cured Dental Adhesive Resin for Mounting Electrodes or Microdialysis Probes in Chronic Experiments

Published on: July 30, 2007

15.8K

Area of Science:

  • Biomaterials Science
  • Dental Materials Science
  • Polymer Chemistry

Background:

  • Dental composite restorations are susceptible to degradation in acidic oral environments.
  • Current dental adhesives lack inherent pH-modulating capabilities.
  • Amino acid integration offers a novel strategy for enhancing dental material performance.

Purpose of the Study:

  • To investigate the impact of lysine incorporation into dental adhesives.
  • To evaluate effects on polymerization kinetics, pH neutralization, mechanical, and thermal properties.
  • To assess lysine leaching and its influence on adhesive performance.

Main Methods:

  • Lysine was added to resin formulations (2.5 and 5.0wt%) containing 2-hydroxyethyl-methacrylate (HEMA) and Bisphenol A glycerolate dimethacrylate (BisGMA).
  • Photopolymerization kinetics, neutralization capacity, mechanical properties (storage modulus), thermal properties (Tg), and lysine release were analyzed.
  • Control and experimental adhesives were compared under various conditions.

Main Results:

  • A 2.5wt% lysine concentration significantly increased the degree of conversion.
  • Experimental adhesives effectively neutralized acidic microenvironments.
  • Lysine release was approximately 50% within one month; storage modulus remained unaffected under dry, physiological conditions.
  • The control adhesive exhibited a higher glass transition temperature (Tg) due to a more compact structure.

Conclusions:

  • Lysine incorporation into dental adhesives shows potential for pH modulation, contributing to improved composite restoration longevity.
  • This study provides a foundation for using amino acids or peptides in dental adhesives for enhanced bioactivity and pH control.
  • Lysine-modified adhesives offer a promising approach to address challenges in dental restorative materials.