Related Experiment Video
Updated: Feb 5, 2026

Author Spotlight: Enhancing Dental Pulp Research with Improved Mouse Models
Published on: October 27, 2023
Efficacy of two mouth rinse sprays in inhibiting
Dalia Mamdouh Talaat1, Aly Abd El-Aziz Sharaf1, Mona Abd El-Moneim Ghoneim2
1Faculty of Dentistry, Alexandria University, Egypt.
Objective:
To compare the efficacy of two types of mouth rinse sprays (Periogard and Plax) in inhibiting the growth of Streptococcus mutans (S. mutans) on toothbrush bristles used by children.
Methods:
An experimental comparative study was performed. The sample included 60 children aged 6-8 years with high caries index. Children were divided randomly into 3 groups (20 each) according to materials applied on toothbrush. Each group was further subdivided into 2 subgroups A and B (10 each) according to the laboratory standards for processing microbiological specimens. Each toothbrush was placed in phosphate buffered saline, vortexed then serially diluted. Mitis salivarius bacitracin (MSB) agar plates were inoculated and incubated for 48 h. S. mutans colonies were identified by morphology, gram stain and biochemical tests.
Results:
Statistically, significant difference was observed between the three groups either when toothbrushes were processed immediately or when processed after 24 h. Group I showed highest bacterial count followed by group III whereas group II showed least bacterial count. Bacterial counts were significantly decreased by time in group I and group III while in group II no significant decrease as both subgroups showed very low bacterial count.
Conclusions:
Although both mouth rinses were effective against S. mutans toothbrush contamination, chlorhexidine gluconate proved to be better.
Related Concept Videos
Assessment of the Mouth
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Feedback Inhibition
Self-Efficacy
Enzyme Inhibition
Inhibition of Cdk Activity
Dose-Response Relationship: Potency and Efficacy

