Related Experiment Video
Updated: Feb 5, 2026

Assessment of Bone Fracture Healing Using Micro-Computed Tomography
Published on: December 9, 2022
Spiral scanning imaging and quantitative calculation of the 3-dimensional screw-shaped bone-implant interface on
Jung-Yoo Chesaria Choi1, Cham Albert Choi2, In-Sung Luke Yeo3
1Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea.
Purpose:
Bone-to-implant contact (BIC) is difficult to measure on micro-computed tomography (CT) because of artifacts that hinder accurate differentiation of the bone and implant. This study presents an advanced algorithm for measuring BIC in micro-CT acquisitions using a spiral scanning technique, with improved differentiation of bone and implant materials.
Methods:
Five sandblasted, large-grit, acid-etched implants were used. Three implants were subjected to surface analysis, and 2 were inserted into a New Zealand white rabbit, with each tibia receiving 1 implant. The rabbit was sacrificed after 28 days. The en bloc specimens were subjected to spiral (SkyScan 1275, Bruker) and round (SkyScan 1172, SkyScan 1275) micro-CT scanning to evaluate differences in the images resulting from the different scanning techniques. The partial volume effect (PVE) was optimized as much as possible. BIC was measured with both round and spiral scanning on the SkyScan 1275, and the results were compared.
Results:
Compared with the round micro-CT scanning, the spiral scanning showed much clearer images. In addition, the PVE was optimized, which allowed accurate BIC measurements to be made. Round scanning on the SkyScan 1275 resulted in higher BIC measurements than spiral scanning on the same machine; however, the higher measurements on round scanning were confirmed to be false, and were found to be the result of artifacts in the void, rather than bone.
Conclusions:
The results of this study indicate that spiral scanning can reduce metal artifacts, thereby allowing clear differentiation of bone and implant. Moreover, the PVE, which is a factor that inevitably hinders accurate BIC measurements, was optimized through an advanced algorithm.
More Related Videos
04:24Proper Positioning and Restraint of a Rat Hind Limb for Focused High Resolution Imaging of Bone Micro-architecture Using In Vivo Micro-computed Tomography
Published on: November 22, 2017
11:45Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography
Published on: May 26, 2015
Related Concept Videos
Imaging Studies III: Computed Tomography
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Protein-protein Interfaces
Leaky Scanning
Screw: Problem Solving
To evaluate the...
Self-Locking Screw
A square-threaded screw jack carrying a load is considered self-locking if the screw retains its position even after the moment applied to it is removed.