Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is Metabolism?00:52

What is Metabolism?

131.9K
Overview
131.9K
Carbohydrate Metabolism01:36

Carbohydrate Metabolism

14.3K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
14.3K
Overview of Metabolism01:40

Overview of Metabolism

38.4K
Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
38.4K
Regulation of Metabolism01:19

Regulation of Metabolism

11.6K
Cellular needs and conditions vary from cell to cell and change within individual cells over time. For example, the required enzymes and energetic demands of stomach cells are different from those of fat storage cells, skin cells, blood cells, and nerve cells. Furthermore, a digestive cell works much harder to process and break down nutrients during the time that closely follows a meal compared with many hours after a meal. As these cellular demands and conditions vary, so do the amounts and...
11.6K
Metabolic Rate01:25

Metabolic Rate

1.3K
The human body is a powerhouse of energy, with every cell performing numerous functions that require energy. This energy production and consumption is measured by the metabolic rate, which quantifies the total heat generated by all the body's chemical reactions and mechanical work. This measurement helps to determine the rate of kilocalorie (kcal) consumption needed to fuel all ongoing activities.
The Basal Metabolic Rate (BMR) measures the energy expended at rest.
Several factors influence...
1.3K
Introduction to Metabolism01:30

Introduction to Metabolism

2.9K
Metabolism encompasses all biochemical reactions in a living organism, facilitating both the breakdown and synthesis of biomolecules. These metabolic processes are categorized into catabolic and anabolic pathways, which operate in a coordinated manner to ensure energy balance and cellular function.Catabolic Pathways and Energy ReleaseCatabolic pathways involve the breakdown of complex macromolecules such as carbohydrates, lipids, and proteins into smaller structures like monosaccharides, fatty...
2.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neutrophil-derived itaconate facilitates tiered pulmonary inflammation via Kdm5b-associated epigenetic remodeling in alveolar macrophages.

Cell reports·2026
Same author

Emerging complexities of phospholipid metabolism in adipose tissue.

Molecules and cells·2026
Same author

Brown adipose tissue remains hot.

Nature reviews. Endocrinology·2025
Same author

A shift in PKM2 oligomeric state instructs adipocyte inflammatory potential.

JCI insight·2025
Same author

Rag GTPases Suppress Renal Cystic Disease by Inhibiting TFEB Independently of mTORC1.

bioRxiv : the preprint server for biology·2025
Same author

<i>Rlim</i> coordinates diurnal regulation of food intake and thermogenesis.

bioRxiv : the preprint server for biology·2025

Related Experiment Video

Updated: Feb 5, 2026

Infrared Thermography for the Detection of Changes in Brown Adipose Tissue Activity
08:16

Infrared Thermography for the Detection of Changes in Brown Adipose Tissue Activity

Published on: September 28, 2022

2.9K

Brown Adipose Tissue Development and Metabolism.

Su Myung Jung1, Joan Sanchez-Gurmaches2,3, David A Guertin4,5,6

  • 1Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA.

Handbook of Experimental Pharmacology
|September 12, 2018
PubMed
Summary

Brown adipose tissue (BAT) is crucial for thermoregulation and metabolic health in adults. Research is exploring its potential to treat obesity and type 2 diabetes by stimulating energy expenditure.

Keywords:
AdipogenesisBeige adipocyteBrite adipocyteBrown adipose tissueDevelopmentGlucose and lipid metabolismLineage tracingProgenitor cellsThermogenesisUcp1

More Related Videos

Author Spotlight: Illuminating New Avenues for Adipose Tissue Metabolism and Disease Prevention
02:55

Author Spotlight: Illuminating New Avenues for Adipose Tissue Metabolism and Disease Prevention

Published on: October 6, 2023

2.0K
Cerenkov Luminescence Imaging of Interscapular Brown Adipose Tissue
06:28

Cerenkov Luminescence Imaging of Interscapular Brown Adipose Tissue

Published on: October 7, 2014

13.8K

Related Experiment Videos

Last Updated: Feb 5, 2026

Infrared Thermography for the Detection of Changes in Brown Adipose Tissue Activity
08:16

Infrared Thermography for the Detection of Changes in Brown Adipose Tissue Activity

Published on: September 28, 2022

2.9K
Author Spotlight: Illuminating New Avenues for Adipose Tissue Metabolism and Disease Prevention
02:55

Author Spotlight: Illuminating New Avenues for Adipose Tissue Metabolism and Disease Prevention

Published on: October 6, 2023

2.0K
Cerenkov Luminescence Imaging of Interscapular Brown Adipose Tissue
06:28

Cerenkov Luminescence Imaging of Interscapular Brown Adipose Tissue

Published on: October 7, 2014

13.8K

Area of Science:

  • Metabolic Physiology
  • Adipocyte Biology
  • Thermoregulation

Background:

  • Brown adipose tissue (BAT) plays a key role in thermoregulation, especially in infants and small mammals.
  • Recent discoveries highlight BAT's significance for metabolic fitness in adult humans.
  • The energy-expending capacity of active brown fat is a target for metabolic disease therapies.

Purpose of the Study:

  • To review current knowledge on the development and metabolic pathways of thermogenic adipocytes.
  • To discuss the phenomenon of white fat browning and its implications.
  • To identify areas for future research into brown fat's functions.

Main Methods:

  • Literature review of developmental and metabolic pathways.
  • Analysis of research on brown fat biology and white fat browning.
  • Synthesis of current understanding and identification of knowledge gaps.

Main Results:

  • Brown fat development and function are complex processes.
  • White fat can be converted into brown-like adipocytes with thermogenic potential.
  • Significant gaps remain in understanding brown fat's full range of functions.

Conclusions:

  • Brown adipose tissue is a promising target for treating metabolic disorders.
  • Further research into thermogenic adipocyte pathways is essential.
  • Understanding brown fat's diverse roles will drive future therapeutic strategies.