[Studies on Chemical Constituents from the Fruit of Swietenia macrophylla]

To study the chemical constituents from the fruit of Swietenia macrophylla.

The chemical constituents were extracted and isolated by silica gel, Sephadex LH-20. The chemical structures of components were further elucidated by the physicochemical characters and MS,NMR spectral data.

17 compounds were isolated and identified as swietenine( 1),swietenine acetate( 2),febrifugine( 3),khayasin T( 4),3-O-tigloyl-6-O-acetylswietenolide( 5),3-O-tigloylswietenolide( 6),3,6-O,O-diacetylswietenolide( 7),fissinolide( 8),3-O-acetylswietenolide( 9), proceranolide( 10),swietenolide( 11),swietemahonin E( 12),swietemahonin F( 13),7-deacetoxy-7-oxogedunin( 14),secomahoganin( 15),altissimanin B( 16),ororatone( 17).

Compounds3,5,8 ~ 10,16,17 are isolated from this plant for the first time.