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Pregnancy and Naltrexone Pharmacotherapy

Cresta W Jones1, Mishka Terplan

  • 1Department of Obstetrics, Gynecology and Women's Health, University of Minnesota Medical School, Minneapolis, Minnesota; and Virginia Commonwealth University, Richmond, Virginia.

Obstetrics and Gynecology
|September 12, 2018
PubMed

A 25-year-old woman, gravida 3 para 2 at 12 weeks of gestation, with two prior cesarean deliveries, presents for prenatal care. She is in treatment for opioid use disorder on extended-release naltrexone injection, with a history of opioid overdose, relapse, and poor treatment adherence on methadone and buprenorphine. She asks, "Is it safe for my baby if I continue on this medication? How will you manage my postoperative pain?"

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