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Published on: August 12, 2021
Surgery for Tumors of the Heart
Bobby Yanagawa1, Amine Mazine2, Edward Y Chan3
1Division of Cardiac Surgery, Department of Surgery, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.
Abstract:
Most surgeons will encounter only a handful of primary cardiac tumors outside of myxomas. Approximately 3 quarters of primary cardiac tumors are benign and 1 quarter is malignant. In most cases, cardiac tumors are silent but when symptoms do occur, they are primarily determined by tumor size and anatomical location, not by histopathology. The diagnosis and preoperative imaging relies heavily on multimodal imaging including echocardiography, computed tomography, magnetic resonance imaging, and coronary angiography. Surgical resection is the most common treatment for most simple primary cardiac tumors and for some complex benign tumors. Surgical resection of primary cardiac tumors frequently involves the need for complex cardiac reconstruction, particularly when malignant. Secondary tumors to the heart are 30 times more frequent than primary cardiac tumors, and their incidence is increasing, largely as a result of advances in cancer diagnosis and therapy. Surgical resection is feasible in only a small fraction of highly-selected patients with secondary tumors to the heart. For complex benign tumors-such as paraganglioma or large fibromas-and all primary and secondary malignant tumors, a multidisciplinary cardiac tumor team review in experienced centers of excellence is recommended.
Insights
Primary cardiac tumors are usually benign and diagnosed with imaging. Surgical resection is common for benign tumors, while malignant tumors and complex cases require multidisciplinary team review.
Area of Science:
- Cardiovascular Surgery
- Surgical Oncology
- Diagnostic Imaging
Background:
- Primary cardiac tumors are rare, with most being benign (75%).
- Symptoms depend on tumor size and location, not histology.
- Secondary cardiac tumors are far more common than primary ones.
Purpose of the Study:
- To review the diagnosis and management of primary and secondary cardiac tumors.
- To highlight the role of imaging and surgical resection.
- To emphasize the importance of multidisciplinary teams for complex cases.
Main Methods:
- Multimodal imaging: echocardiography, CT, MRI, coronary angiography.
- Surgical resection for benign and some complex primary tumors.
- Review of treatment strategies for primary and secondary cardiac tumors.
Main Results:
- Benign tumors are more common than malignant primary cardiac tumors.
- Surgical resection is the primary treatment for most primary tumors.
- Malignant tumors and secondary tumors often require complex reconstruction or are unresectable.
Conclusions:
- Multimodal imaging is crucial for diagnosis and surgical planning.
- Surgical resection is the mainstay for benign primary cardiac tumors.
- Complex benign, malignant, and secondary cardiac tumors necessitate expert multidisciplinary team evaluation.
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