Related Experiment Video
Updated: Feb 5, 2026
08:45
Cerenkov Luminescence Imaging CLI for Cancer Therapy Monitoring
Published on: November 13, 2012
14.3K
Nano-Based Therapy for Treatment of Skin Cancer
Sadaf J Gilani1, Mohammed A Jahangir2, Chandrakala2
1College of Pharmacy, Aljouf University, Aljouf, Sakaka, Saudi Arabia.
Recent Patents on Anti-Infective Drug Discovery
|September 13, 2018
Summary
Topical nanoformulations, particularly lipid-based ones, offer improved chemotherapy for skin cancer by enhancing drug delivery and reducing side effects. This approach targets cancer cells more effectively for better treatment outcomes.
Area of Science:
- Oncology
- Nanotechnology
- Dermatology
Background:
- Skin cancer is a prevalent global malignancy.
- Conventional treatments like chemotherapy have limitations due to undesirable side effects.
- Topical nanoformulations are emerging as a promising alternative for skin cancer treatment.
Purpose of the Study:
- To review recent advancements in nano-sized topical lipid formulations for skin cancer treatment.
- To highlight the benefits of encapsulated drugs in chemotherapy.
- To explore the potential of these formulations in improving treatment efficacy and reducing side effects.
Main Methods:
- Focus on lipid-based nanoformulations for topical delivery.
- Discusses the collective action of lipid components in overcoming biological barriers.
- Explores targeted accumulation of nanoformulations in disease-target cells.
Main Results:
- Lipid-based nanoformulations demonstrate potential for targeted delivery of therapeutic agents.
- These formulations can overcome biological barriers to reach cancer cells.
- Recent developments show promise in nano-sized topical lipid formulation approaches for skin cancer.
Conclusions:
- Topical lipid formulations combined with chemotherapy offer enhanced target specificity and controlled drug release.
- Real-time monitoring capabilities can further improve treatment outcomes.
- The goal is to diminish side effects, reduce costs, and increase chemotherapy efficiency.
Related Concept Videos
01:30Skin Cancer
5.9K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.9K
02:49Cancer Therapies
10.2K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
10.2K
02:57Targeted Cancer Therapies
8.9K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
8.9K
02:56Treatment Resistant Cancers
3.8K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.8K
00:59Gene Therapy
27.6K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
27.6K
01:16Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
625
Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
625