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Research integrity and the law that never was
Martin Mayer1,2
1Innovations and Evidence-Based Medicine Development, EBSCO Health, Ipswich, Massachusetts, USA.
BMJ Evidence-Based Medicine
|September 13, 2018
Summary
Publication bias and lack of research transparency threaten evidence-based medicine. Recent developments offer hope for resolution, but their long-term effectiveness remains to be seen.
Area of Science:
- Medical Research Integrity
- Evidence-Based Practice
Background:
- Publication bias and inadequate research transparency undermine evidence-based medicine.
- These critical issues have persisted for an extended period with insufficient regulatory action.
Purpose of the Study:
- To chronicle the history of publication bias and research transparency issues.
- To review past failed attempts at resolution.
- To examine current and proposed solutions for lasting change.
Main Methods:
- Historical analysis of publication bias and research transparency.
- Review of regulatory efforts and their efficacy.
- Assessment of recent developments and ongoing initiatives.
Main Results:
- Evidence-based medicine is significantly impacted by publication bias and lack of transparency.
- Past regulatory efforts have been insufficient to resolve these problems.
- Recent advancements show promise, but their ultimate success is uncertain.
Conclusions:
- Addressing publication bias and research transparency is crucial for the integrity of evidence-based medicine.
- While recent efforts are encouraging, sustained vigilance and evaluation are necessary.
- The long-term resolution of these issues will depend on the continued efficacy of implemented measures.
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