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Choroidal thickness increase after micropulse transscleral cyclophotocoagulation.

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MicroPulse Transscleral Cyclophotocoagulation (MP-TSCPC) effectively lowers intraocular pressure (IOP) in glaucoma patients. Responsive patients showed increased choroidal thickness, indicating enhanced uveoscleral outflow post-treatment.

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Area of Science:

  • Ophthalmology
  • Medical Technology

Background:

  • Glaucoma is a leading cause of irreversible blindness due to optic nerve damage.
  • MicroPulse Transscleral Cyclophotocoagulation (MP-TSCPC) is a treatment option for glaucoma patients.
  • Understanding MP-TSCPC's efficacy and mechanisms is crucial for managing glaucoma.

Purpose of the Study:

  • To evaluate the clinical experience and OCT findings of glaucoma patients treated with MP-TSCPC.
  • To assess the impact of MP-TSCPC on intraocular pressure (IOP) and choroidal thickness.

Main Methods:

  • Prospective study involving twenty-two glaucoma patients undergoing MP-TSCPC under local anesthesia.
  • MP-TSCPC utilized 810nm infrared diode micropulse laser (2000mW, 31.3% duty cycle, 80-130s per hemisphere).
  • Macular OCT scans measured foveolar choroidal thickness; IOP was monitored for six months post-treatment.

Main Results:

  • Mean IOP decreased from 35.23 mmHg preoperatively to 17.73 mmHg at 1 week post-treatment (49.67% reduction).
  • Responsive patients exhibited a mean 7.3% increase in choroidal thickness, sustained for three months.
  • Non-responsive patients showed no significant change or a decrease in choroidal thickness.

Conclusions:

  • MP-TSCPC significantly reduces IOP in glaucoma patients.
  • Increased choroidal thickness correlates with IOP reduction, suggesting enhanced uveoscleral outflow as a treatment mechanism.
  • MP-TSCPC is a viable option for glaucoma management, with OCT providing insights into treatment response.