Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Binet's Contribution to Measures of Intelligence01:23

Binet's Contribution to Measures of Intelligence

1.7K
Alfred Binet, along with his student Théophile Simon, was tasked by the French Ministry of Education in 1904 to create a method for identifying students who struggled to learn through conventional classroom instruction. This initiative aimed to address overcrowding by placing such students in specialized schools. Binet and Simon developed an intelligence test comprising 30 tasks, ranging from simple commands, like touching one's nose or ear, to more complex tasks, such as drawing...
1.7K
Wechsler's Contribution to Measures of Intelligence01:23

Wechsler's Contribution to Measures of Intelligence

2.1K
David Wechsler, a psychologist who worked with World War I veterans, developed a significant IQ test in 1939 called the Wechsler-Bellevue Intelligence Scale. This test was innovative because it combined several subtests that measured both verbal and nonverbal skills, reflecting Wechsler's belief that intelligence is a global capacity involving purposeful action, rational thinking, and effective interaction with the environment. This test later evolved into the Wechsler Adult Intelligence...
2.1K
Quality Control01:05

Quality Control

2.6K
Quality control is one of the three cyclical quality assurance activities that help keep a system under statistical control. Typical quality control activities include creating quality control charts, conducting proficiency testing, and documenting and archiving results.
Quality control helps track data, visualize trends, and identify variations, making it easier to detect deviations that may affect the accuracy of an analysis. One way to do this is by generating a quality control chart, which...
2.6K
Quality Assurance01:19

Quality Assurance

2.3K
Quality assurance is the overarching term used to describe the activities employed to ensure the proper performance of a system. These activities can be classified into three categories: quality control, quality assessment, and internal corrective measures. Typically, these activities work cyclically: quality control is performed before and during the analysis, while quality assessment occurs during and after the investigation. Internal corrective measures are implemented based on the findings...
2.3K
Quality of Water01:19

Quality of Water

570
In concrete preparation, the quality of water is paramount as it affects the strength and durability of the concrete. Potable water is usually preferred; however, it must not have excessive sodium or potassium to prevent compromising the concrete's integrity. Water quality is typically evaluated based on impurities such as dissolved solids, chlorides, and sulfates, and its pH value is ideally between 6 and 8. Even slightly acidic natural water may be acceptable unless it contains harmful...
570
Transcription Factors02:16

Transcription Factors

82.8K
Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
82.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Metabolic imaging for gamete and embryo assessment through advanced microscopy technologies: a novel avenue for artificial intelligence?

Human reproduction (Oxford, England)·2026
Same author

Clinical embryology in the United States: current landscape and considerations for professional development and standardization.

Fertility and sterility·2026
Same author

Unified Transcriptome and Mechanics Map of the Intact Mammalian Preimplantation Embryo In Situ.

bioRxiv : the preprint server for biology·2026
Same author

Can Cell-Free DNA in the Culture Medium Predict the Chromosomal Constitution of Preimplantation Embryos? Final Results from a Multicenter Study with 2539 Blastocysts.

Genes·2026
Same author

From determinism to probability: integrating artificial intelligence into male infertility genetics.

Journal of assisted reproduction and genetics·2026
Same author

Microfluidic automation improves oocyte recovery from follicular fluid of patients undergoing in vitro fertilization.

Nature medicine·2026

Related Experiment Video

Updated: Feb 5, 2026

Fabrication of Silica Ultra High Quality Factor Microresonators
07:51

Fabrication of Silica Ultra High Quality Factor Microresonators

Published on: July 2, 2012

16.9K

Paternal factors contributing to embryo quality.

Stacy Colaco1, Denny Sakkas2

  • 1Molecular and Cellular Biology Laboratory, Indian Council of Medical Research-National Institute for Research in Reproductive Health, JM Street, Parel, Mumbai, 400012, India. stacy.colaco@gmail.com.

Journal of Assisted Reproduction and Genetics
|September 13, 2018
PubMed
Summary

Paternal factors significantly impact embryo quality and live birth rates in assisted reproductive technologies (ART). Evaluating sperm parameters like DNA integrity and genetic factors is crucial for successful ART outcomes.

Keywords:
DNA fragmentationEmbryoHistoneMethylationPaternal factorsProtaminesSperm chromatinSperm epigeneticsY chromosome microdeletions

More Related Videos

Stable Isotope In-Vivo Labeling for Mass-Spectrometry Identification of Paternal Metabolites Transferred from Sperm to Oocyte During Fertilization
05:55

Stable Isotope In-Vivo Labeling for Mass-Spectrometry Identification of Paternal Metabolites Transferred from Sperm to Oocyte During Fertilization

Published on: June 17, 2025

875
Using a Comparative Species Approach to Investigate the Neurobiology of Paternal Responses
07:59

Using a Comparative Species Approach to Investigate the Neurobiology of Paternal Responses

Published on: September 19, 2011

13.1K

Related Experiment Videos

Last Updated: Feb 5, 2026

Fabrication of Silica Ultra High Quality Factor Microresonators
07:51

Fabrication of Silica Ultra High Quality Factor Microresonators

Published on: July 2, 2012

16.9K
Stable Isotope In-Vivo Labeling for Mass-Spectrometry Identification of Paternal Metabolites Transferred from Sperm to Oocyte During Fertilization
05:55

Stable Isotope In-Vivo Labeling for Mass-Spectrometry Identification of Paternal Metabolites Transferred from Sperm to Oocyte During Fertilization

Published on: June 17, 2025

875
Using a Comparative Species Approach to Investigate the Neurobiology of Paternal Responses
07:59

Using a Comparative Species Approach to Investigate the Neurobiology of Paternal Responses

Published on: September 19, 2011

13.1K

Area of Science:

  • Reproductive biology
  • Genetics
  • Assisted Reproductive Technologies (ART)

Background:

  • Advanced maternal and paternal age reduces fertility, leading couples to seek ART.
  • Embryo quality, crucial for ART success, depends on both oocyte and sperm quality.
  • Sperm's contribution to embryo quality requires comprehensive evaluation.

Purpose of the Study:

  • To review the impact of paternal genetic factors on embryo quality and development.
  • To highlight the under-explored role of sperm quality in ART outcomes.

Main Methods:

  • Literature review assessing genetic factors of paternal origin.
  • Exploration of sperm aneuploidy, chromatin structure, DNA fragmentation, protamines/histones, epigenetics, and Y chromosome microdeletions.

Main Results:

  • Sperm aneuploidy negatively affects embryo quality.
  • Sperm chromatin structure and DNA fragmentation impact embryo development.
  • Protamine/histone roles, epigenetic profiles, and Y chromosome microdeletions are linked to reduced embryo quality.

Conclusions:

  • Assessing spermatozoal parameters is vital for embryo development and live birth.
  • Need for standardized protocols to evaluate sperm factors affecting embryo quality due to test heterogeneity.