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Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
The Borole Route to Reactive Pentafluorophenyl-Substituted Diboranes(4)
Fang Ge1,2, Xin Tao1, Constantin G Daniliuc1
1Organisch-Chemisches Institut, Westfälische Wilhelms-Universität Münster, Corrensstr. 40, 48149, Münster, Germany.
Abstract:
The β-borylborole 3 adds phenylacetylene in a [4+2]-cycloaddition to give the boryl-substituted 7-boranorbornadiene derivative 4 b. Thermolysis (60 °C) results in a rearrangement with B-B coupling to give the tetraaryldiborane(4) 6 b. It splits dihydrogen with cleavage of the B-B bond. With the terminal acetylene 1-pentyne the diborane(4) compound 6 b undergoes a rare 1,1-diboration reaction to yield the respective geminal diborylalkene product 14.
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