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Development of nanoparticulate systems with action in breast and ovarian cancer: nanotheragnostics

Fabiana de Sousa Cunha1, Laise Nayra Dos Santos Pereira2, Thâmara Pryscilla de Costa E Silva2

  • 1a Departamento de Química, Campus Poeta Torquato Neto , Universidade Estadual do Piauí , Teresina , Brazil.

Journal of Drug Targeting
|September 13, 2018
PubMed

Insights

Nanoparticulate systems offer a promising approach to enhance cancer therapy by improving drug delivery and efficacy for breast and ovarian cancers. This review explores various nanosystems for improved therapeutic outcomes.

Area of Science:

  • Oncology
  • Nanotechnology
  • Pharmacology

Background:

  • Nanoparticulate systems are increasingly recognized for their potential in cancer treatment.
  • Conventional chemotherapy faces challenges like limited therapeutic index and systemic toxicity.
  • Nanoparticles offer unique characteristics for targeted cancer therapy.

Purpose of the Study:

  • To review nanosystems utilizing nanoparticles for treating breast and ovarian cancers.
  • To highlight the advantages of nanoparticles in cancer drug delivery.
  • To examine how nanocarriers modify drug pharmacokinetics for targeted delivery.

Main Methods:

  • Literature review of existing studies on nanoparticulate systems in cancer therapy.
  • Analysis of nanocarrier drug delivery systems for breast and ovarian cancer.
  • Examination of pharmacokinetic modifications induced by nanocarriers.

Main Results:

  • Nanoparticles can enhance the therapeutic index of anticancer drugs.
  • Nanocarriers facilitate specific drug delivery to tumor cells.
  • Various nanocarrier systems are described in the literature for cancer treatment.

Conclusions:

  • Nanoparticulate systems represent a significant advancement in treating breast and ovarian cancers.
  • Targeted drug delivery via nanoparticles improves treatment efficacy and potentially reduces side effects.
  • Further research into nanosystems holds promise for overcoming limitations in current cancer therapies.
Keywords:
Nanomedicinebreast cancernanocarriersovarian cancertheranostics

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