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Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
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Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

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Antibiotic-Resistant Bacteria and the Use of Novel Antibiotics in Children

Evelyn Lai, Jeffrey M Bender

    Pediatric Annals
    |September 13, 2018
    PubMed

    Insights

    Antibiotic-resistant bacterial infections in children are increasing globally, challenging pediatric caregivers. This review explores challenges, new antibiotics, and strategies to combat these infections in pediatric populations.

    Area of Science:

    • Pediatric infectious diseases
    • Antimicrobial resistance
    • Pharmacology

    Background:

    • Rising incidence of antibiotic-resistant bacterial infections in children worldwide.
    • Significant challenges for pediatric caregivers in treating these infections.
    • Depletion of the antibiotic armamentarium against resistant pathogens.

    Purpose of the Study:

    • To review the challenges faced by clinicians treating pediatric resistant bacterial infections.
    • To examine emerging antibiotic options for pediatric use.
    • To discuss alternative strategies for combating pediatric resistant infections.

    Main Methods:

    • Literature review of current challenges and treatments.
    • Analysis of newer antibiotic agents for pediatric application.
    • Discussion of non-antibiotic therapeutic approaches.

    Main Results:

    • Identified key clinical challenges in managing pediatric resistant infections.
    • Highlighted promising newer antibiotics and their potential role.
    • Explored adjunctive therapies and infection control measures.

    Conclusions:

    • An informed and concerted effort is crucial to address the growing problem of pediatric antibiotic resistance.
    • Continued research and strategic implementation of new treatments are necessary.
    • Multifaceted approaches are required to effectively combat resistant bacteria in children.

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