Preventing Cognitive Decline in Black Individuals With Mild Cognitive Impairment: A Randomized Clinical Trial
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View abstract on PubMed
Summary
This summary is machine-generated.Behavioral activation significantly reduced memory decline in Black individuals with mild cognitive impairment (MCI). This intervention may help prevent dementia and reduce health disparities.
Area Of Science
- Gerontology and Cognitive Health
- Behavioral Interventions for Cognitive Decline
Background
- Mild cognitive impairment (MCI) signifies a transitional phase from normal aging to dementia, posing a significant risk for progressive cognitive deterioration.
- Preventing cognitive decline is a critical public health objective, particularly given the disproportionately higher rates of dementia in Black individuals.
Purpose Of The Study
- To evaluate the efficacy of behavioral activation in preventing cognitive and functional decline over a 2-year period in Black individuals diagnosed with MCI.
Main Methods
- A single-center, single-masked, attention-controlled randomized clinical trial involving 221 eligible Black participants aged over 65 with amnestic MCI.
- Participants were randomized to either behavioral activation (increasing cognitive, physical, and social activity) or a supportive therapy control group.
- Cognitive decline was assessed using the Hopkins Verbal Learning Test-Revised, and functional decline was also monitored over 24 months.
Main Results
- Behavioral activation demonstrated a significant reduction in the incidence of memory decline over 2 years compared to supportive therapy (1.2% vs. 9.3%).
- Participants in the behavioral activation group maintained stable everyday function, while the supportive therapy group showed functional decline.
- While behavioral activation showed fewer falls, rates of emergency department visits, hospitalizations, and deaths were comparable between groups.
Conclusions
- Behavioral activation emerged as an effective intervention for preventing both cognitive and functional decline in Black individuals with MCI.
- The findings suggest that behavioral activation could be a valuable strategy for mitigating cognitive aging and potentially reducing dementia health disparities.
- Further research is warranted to confirm these findings and explore the broader applicability of behavioral activation in diverse populations.
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