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Effectiveness of D-mannose,

Riccardo Milandri1, Matteo Maltagliati1, Tommaso Bocchialini1

  • 1Department of Urology, University of Modena and Reggio Emilia, Modena, Italy.

Urologia
|September 14, 2018
PubMed
Summary
This summary is machine-generated.

This study found that a phytotherapeutic product containing D-mannose, Hibiscus sabdariffa, and Lactobacillus plantarum effectively reduced urinary tract infections and bacteriuria in women following urodynamic examinations.

Keywords:
D-mannoseElliroseUrodynamic studyurinary tract recurrent infections

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Area of Science:

  • Urology
  • Microbiology
  • Pharmacology

Background:

  • Urodynamic studies are invasive procedures that carry a risk of lower urinary tract infections.
  • Preventing these infections involves risk factor avoidance and antimicrobial/non-antimicrobial prophylaxis.

Purpose of the Study:

  • To evaluate the efficacy of a phytotherapeutic product in preventing infectious events post-urodynamic examination.
  • The product contains D-mannose, Hibiscus sabdariffa, and Lactobacillus plantarum.

Main Methods:

  • 100 female patients undergoing invasive urodynamic procedures were enrolled.
  • A 14-day course of D-mannose, H. sabdariffa, and L. plantarum was administered post-procedure.
  • Urine cultures and symptom assessments were used to detect urinary tract infections.

Main Results:

  • 13% of patients developed urinary tract infections (UTIs), with 9 in those with recurrent infections and 4 in those without.
  • 10 cases were asymptomatic bacteriuria; 3 women reported symptoms requiring antibiotics.
  • Constipation, post-voiding residue, and pelvic organ prolapse were noted in some UTI cases.

Conclusions:

  • The phytotherapeutic combination of D-mannose, H. sabdariffa, and L. plantarum effectively reduced the risk of bacteriuria and UTIs in women after invasive urodynamic tests.
  • The product was well-tolerated and affordable, with no reported side effects.