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Updated: Feb 5, 2026

Assaying for Inorganic Polyphosphate in Bacteria
Published on: January 21, 2019
Inorganic Polyphosphate and Cancer
E V Kulakovskaya1, M Yu Zemskova1,2, T V Kulakovskaya3
1Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia.
Abstract:
This review presents data on the relationship between inorganic polyphosphate metabolism and carcinogenesis including participation of polyphosphates in the regulation of activity of mTOR and other proteins involved in carcinogenesis, the role of h-prune protein (human polyphosphatase) in cell migration and metastasis formation, the prospects for using polyphosphates and inhibitors of polyphosphate metabolism enzymes as agents for controlling cell proliferation and migration.
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