Intestinal dysbiosis and hormonal neuroendocrine secretion in the fibromyalgic patient: Relationship and correlations
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Updated: Feb 5, 2026

Mechanisms Underlying Gut Hormone Secretion Using the Isolated Perfused Rat Small Intestine
Published on: February 26, 2019
Giovanni Tomasello1, Margherita Mazzola1,2, Vincenzo Bosco3
1Department of Experimental Biomedicine and Clinical Neuroscience, Section of Human Anatomy, (BIONEC), School of Medicine and Surgery, University of Palermo, Palermo, Italy.
Abstract:
Fibromyalgia is a rheumatic syndrome and its pathogenesis is controversial. The recent literature has placed considerable attention on the link between alteration of the intestinal microbiota and fibromyalgia, emphasizing the close connection between the neuroenteric system and the CNS. This study aims to evaluate the probable relationship between intestinal dysbiosis and altered secretion of hormones and vitamins such as cortisol, serotonin, Vitamin D and thyroid hormones in a patient with fibromyalgia.
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