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Author Spotlight: Investigating Fungal Pathogenicity Mechanisms in Maize
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Top-ten papers in fungal infection (2015-2017)

P Puerta-Alcalde1, C Cardozo, A Soriano

  • 1Pedro Puerta-Alcalde, MD. Infectious Diseases Department, Hospital Clínic; Carrer Villarroel 170, 08036, Barcelona, Spain. pedro.puerta84@gmail.com.

Revista Espanola De Quimioterapia : Publicacion Oficial De La Sociedad Espanola De Quimioterapia
|September 14, 2018
PubMed

Insights

Recent fungal infection research highlights the rise of Candida auris, a resistant pathogen, and the impact of biologic therapies. New treatments like isavuconazole show promise for difficult fungal infections.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Clinical Research

Background:

  • Fungal infections pose significant global health challenges.
  • Antifungal resistance and treatment-related infections are growing concerns.

Purpose of the Study:

  • To categorize and summarize key developments in fungal infection research from 2016-2017.
  • To identify emerging trends and significant findings in mycology.

Main Methods:

  • Systematic review and clustering of published articles on fungal infections.
  • Analysis of trends in pathogen emergence, treatment modalities, and therapeutic outcomes.

Main Results:

  • Identified Candida auris as a critical nosocomial pathogen with high resistance and mortality.
  • Highlighted increased fungal infections linked to biologic therapies.
  • Noted the approval and efficacy of isavuconazole for specific fungal infections.
  • Summarized advancements in empiric therapy and management of challenging fungal cases.

Conclusions:

  • The landscape of fungal infections is rapidly evolving, demanding attention to emerging pathogens and novel therapeutic strategies.
  • Continued research is crucial for combating antifungal resistance and improving patient outcomes.

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