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[Antimicrobial stewardship programme implementation in a medical ward]

J Ruiz1, M Salavert, P Ramírez

  • 1Jesús Ruiz. Hospital Universitario y Politecnico La Fe. Avenida Fernando Abril Martorell nº106. 46026. Valencia. Spain. jrzrms@gmail.com.

Revista Espanola De Quimioterapia : Publicacion Oficial De La Sociedad Espanola De Quimioterapia
|September 14, 2018
PubMed
Abstract

Insights

Implementing an antimicrobial stewardship programme (ASP) in a medical ward significantly reduced antimicrobial use. This intervention did not negatively impact patient outcomes like length of stay or mortality.

Area of Science:

  • Infectious Diseases
  • Hospital Pharmacy
  • Public Health

Background:

  • Antimicrobial resistance is a growing global health threat.
  • Antimicrobial stewardship programmes (ASP) are crucial for optimizing antimicrobial use.
  • Evaluating ASP effectiveness in diverse medical settings is essential.

Purpose of the Study:

  • To assess the impact of implementing an antimicrobial stewardship programme (ASP) in a heterogeneous medical ward.
  • To quantify changes in antimicrobial consumption post-ASP implementation.
  • To evaluate effects on patient length of stay and mortality.

Main Methods:

  • A prospective intervention study was conducted in a mixed-composition medical ward.
  • An ASP was implemented in September 2014, utilizing prospective audits.
  • Antimicrobial consumption, length of stay, and mortality were compared before and after a two-year ASP intervention period.

Main Results:

  • Antimicrobial consumption decreased significantly from 31.3 to 17.6 DDD/100-stays.
  • Average cost per admission reduced by 23.6% (€161.4 to €123.3).
  • No significant differences were observed in total length of stay, mortality, or incidence of Clostridium difficile infection or candidemia.

Conclusions:

  • ASP implementation in a heterogeneous medical ward effectively reduced antimicrobial usage within a short timeframe.
  • The study demonstrated that ASPs can be implemented without adverse effects on patient outcomes.
  • This highlights the value of ASPs in controlling antimicrobial consumption in complex clinical environments.

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