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Formation of a Toxic Quinoneimine Metabolite from Diclofenac: A Quantum Chemical Study

Muthusamy Ramesh1, Prasad V Bharatam1

  • 1Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Sector-67, S.A.S. Nagar (Mohali)-160 062, India.

Drug Metabolism Letters
|September 14, 2018
PubMed
Abstract

Keywords:
CYP2C9Quantum chemical analysisdiclofenacidiosyncratic toxicitynon-steroidal antiinflammatory drugquinoneimine.

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