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Persistent Vegetative State after Diabetic Ketoacidosis Triggered by an Overdose of Psychotropic Agents
Takeshi Kawashita1, Mikio Nakajima1, Richard H Kaszynski1
1Emergency and Critical Care Center, Tokyo Metropolitan Hiroo Hospital, Japan.
Abstract:
A 28-year-old man with type 1 diabetes mellitus was admitted for shock and coma due to diabetic ketoacidosis. Despite aggressive treatment and management of the patient's underlying clinical issues, the patient remained in a comatose state. Further investigations revealed an excess consumption of psychotropic agents; however, there was no evidence of an insulin overdose. Physicians should be aware that, in patients who are highly dependent upon insulin, an overdose of psychotropic agents can lead to hypoxic-ischemic brain injury.
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