Prevalence of Multidrug-Resistant
Stephen T Odonkor1, Kennedy K Addo2
1Greenhill College, Ghana Institute of Management and Public Administration, Accra, Ghana.
International Journal of Microbiology
|September 14, 2018
Summary
Antimicrobial resistance is a growing threat. This study found poor water quality and high multidrug-resistant E. coli, recommending nitrofurantoin for treating waterborne bacterial infections.
Area of Science:
- Microbiology
- Environmental Science
- Public Health
Background:
- Antimicrobial resistance (AMR) poses a significant threat to global health, complicating infectious disease treatment.
- The presence of antimicrobial-resistant bacteria in water sources raises concerns about public health and disease transmission.
Purpose of the Study:
- To assess the microbiological quality of six different water sources.
- To determine the antibiograms of bacterial isolates, specifically E. coli strains.
- To inform the treatment of waterborne bacterial diseases with updated antibiotic data.
Main Methods:
- Bacterial isolation and identification using API and conventional microbiological techniques.
- Antibiotic susceptibility testing performed via the Kirby-Bauer method.
- Calculation of the multiple antibiotic resistance (MAR) index for multidrug-resistant strains.
Main Results:
- All tested water sources exhibited poor microbiological quality.
- A high prevalence of multidrug-resistant E. coli (49.48%) was detected.
- E. coli isolates displayed significant resistance to penicillin, cefuroxime, erythromycin, and tetracycline.
Conclusions:
- Nitrofurantoin, cefotaxime, amikacin, and gentamicin are recommended for treating waterborne bacterial diseases due to E. coli susceptibility.
- The study highlights the urgent need for improved water quality monitoring and control of antimicrobial resistance.
- Findings provide crucial data for the pragmatic treatment of patients with infections linked to contaminated water sources.
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