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Neuropathy in a petrol sniffer.

D M Hall, J Ramsey, M S Schwartz

    Archives of Disease in Childhood
    |September 1, 1986
    PubMed
    Summary

    Repeated inhalation of petroleum vapor caused severe nerve damage in a child, leading to profound motor neuropathy. Symptoms improved over six months after the exposure stopped, highlighting the neurotoxic effects of petroleum components.

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    Area of Science:

    • Neurology
    • Toxicology
    • Environmental Health

    Background:

    • Petroleum products contain various volatile organic compounds.
    • N-hexane is a known neurotoxin found in petroleum distillates.
    • Occupational and environmental exposure to solvents can pose health risks.

    Observation:

    • A 4-year-old boy presented with significant motor deficits.
    • The child reported repeated, intentional inhalation of petroleum vapor.
    • Clinical examination revealed profound motor neuropathy.

    Findings:

    • Nerve conduction velocity studies showed extreme slowing, indicative of severe peripheral nerve damage.
    • The patient's neurological condition improved gradually over a six-month period.
    • The neuropathy was directly attributed to N-hexane toxicity from petroleum vapor inhalation.

    Implications:

    • This case highlights the potential for severe neurotoxicity in children from deliberate solvent abuse.
    • It underscores the importance of recognizing and managing N-hexane poisoning.
    • Public health awareness regarding the dangers of volatile substance abuse is crucial.

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