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Investigating related factors with mortality rate in patients with postoperative meningitis: One longitudinal follow

Arezoo Chouhdari1,2, Kaveh Ebrahimzadeh1, Omidvar Rezaei1

  • 1Skull Base Research Center, Loghman Hakim Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Iranian Journal of Neurology
|September 14, 2018
PubMed

Insights

Postoperative meningitis (POM) affects 8.9% of neurosurgery patients, with a 50% mortality rate. Key risk factors for death include mechanical ventilation and positive cerebrospinal fluid cultures.

Area of Science:

  • Neurosurgery
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Postoperative meningitis (POM) is a significant cause of death in neurosurgery.
  • Identifying incidence, mortality, and risk factors is crucial for patient outcomes.

Purpose of the Study:

  • To determine the incidence and mortality rates of POM.
  • To identify factors associated with mortality in POM patients.

Main Methods:

  • A 2-year descriptive longitudinal study.
  • Analysis of incidence, mortality, and predictive factors for death.

Main Results:

  • POM incidence was 8.9% with a 50% mortality rate.
  • Factors predicting death included mechanical ventilation, positive CSF culture, and prolonged ICU stay (>7 days).
  • Survival decreased with longer ICU stays.

Conclusions:

  • High POM incidence and mortality necessitate preventative strategies.
  • Targeted interventions are needed to reduce POM-related morbidity and mortality in neurosurgery.
Keywords:
IncidenceMeningitisMortality RatePostoperative ComplicationsRelated Factor

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