Related Experiment Video
Updated: Feb 5, 2026

Induction of Cerebral Arterial Gas Embolism in Rat
Published on: October 18, 2024
Distal embolization of coronary calcified nodule after rotational atherectomy
Norihiro Kobayashi1, Yoshiaki Ito1, Masahiro Yamawaki1
1Department of Cardiology, Saiseikai Yokohama City Eastern Hospital, Yokohama, Japan.
Insights
Rotational atherectomy effectively treats calcified nodules during percutaneous coronary intervention, but carries a risk of distal embolization. Careful consideration of this complication is crucial for successful treatment outcomes.
Area of Science:
- Interventional Cardiology
- Cardiovascular Imaging
- Vascular Biology
Background:
- Percutaneous coronary intervention (PCI) is a common treatment for coronary artery disease.
- Severely calcified lesions, particularly those with calcified nodules, pose significant challenges during PCI.
- Intravascular imaging modalities like optical frequency domain imaging (OFDI) are crucial for characterizing complex lesions.
Observation:
- A 62-year-old man with effort angina presented with a severely calcified lesion in the mid-right coronary artery.
- Pre-procedural OFDI revealed a calcified nodule.
- Initial rotational atherectomy with a 2.0 mm burr increased lumen area, but significant calcification persisted.
Findings:
- Attempting a larger burr (2.25 mm) for rotational atherectomy resulted in distal embolization of the calcified nodule.
- Embolus retrieval failed; balloon angioplasty was performed, but recoil occurred.
- Successful implantation of a drug-eluting stent in the affected segments achieved good expansion, compressing the calcified nodule outside the stent.
Implications:
- Rotational atherectomy can be effective for achieving stent expansion and reducing perforation risk in calcified nodules.
- Distal embolization is a significant complication to anticipate and manage during rotational atherectomy for calcified nodules.
- Careful procedural planning and imaging are essential for optimizing outcomes in complex calcified coronary lesions.
Abstract:
A 62-year-old man with effort angina underwent percutaneous coronary intervention in our hospital. The target lesion was severely calcified at the mid part of the right coronary artery. Pre-procedural intravascular imaging and optical frequency domain imaging showed a calcified nodule at the lesion. We performed rotational atherectomy with a 2.0 mm burr and observed an increase in the lumen area; however, a large amount of calcified nodule persisted. We decided to perform rotational atherectomy with a burr size of 2.25 mm; however, distal embolization of the calcified nodule occurred. We failed to retrieve the embolus; hence, we performed balloon dilatation with a 2.0-mm balloon, which was successfully performed. Yet, the lesion with the embolus immediately recoiled. Finally, a drug-eluting stent was implanted in both the distal lesion with the embolus and the lesion with the calcified nodule. Final coronary angiography showed good results. We confirmed good stent expansion and that calcified nodule was compressed outside the stent. Atherectomy of a calcified nodule is effective at achieving sufficient stent expansion and reducing the risk of vessel perforation. However, we experienced distal embolization of the calcified nodule at the time of rotational atherectomy and so distal embolization should be considered at the time of treatment of calcified nodule.
Related Concept Videos
Pulmonary Embolism I: Introduction
Coronary Circulation
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Kinematic Equations for Rotation
For instance, imagine a point A on a rigid body engaged in circular motion. The translational velocity of this particular point can be calculated by taking the time derivatives of the displacement equation, which essentially measures the...
Rotation of Asymmetric Top
The relationship between the angular momentum of any rigid body and its angular velocity, both of which are vectors, involves the moment of inertia. The moment of inertia is a scalar quantity only for spherically symmetric...
Pulmonary Embolism III: Nursing Management
Rotation with Constant Angular Acceleration - I
Using our intuition, we can begin to see how rotational quantities such as angular displacement, angular velocity, angular acceleration, and time are related to one another. For example, if a flywheel...

