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Updated: Feb 5, 2026

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Giant Cell Tumor of Distal Radius After Open Reduction Internal Fixation for Distal Radius Fracture
Danielle C Marshall1, Roger J Bartolotta1, Roberto A Garcia1
1Department of Orthopedic Surgery (Dr. Marshall), the Department of Radiology (Dr. Bartolotta), and the Department of Pathology (Dr. Garcia), Hospital for Special Surgery, New York, NY; the Department of Pathology, Memorial Sloan Kettering, New York (Dr. Hameed); and the Department of Orthopedic Surgery, Hospital for Special Surgery, New York (Dr. Lorich, Athanasian, and Dr. Fufa).
Case:
A 77-year-old woman presented with volar wrist pain 1.5 years after undergoing distal radius volar locked plating for fracture. Radiographs and CT were notable only for plate prominence, and she was admitted for removal of hardware. Intraoperatively, a large cavitary bone lesion was found. Histopathology demonstrated a giant cell tumor of the bone. Definitive management consisted of wide en bloc resection and osteoarticular allograft reconstruction, which achieved local control and an acceptable clinical result.
Conclusion:
Although not previously described, a giant cell tumor of the bone may develop after fracture. Metal artifact in an area of previous internal fixation can make recognition challenging, but dual-energy CT can be used to decrease this artifact. Local control can be achieved with wide excision and reconstruction.
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