Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pain01:20

Pain

1.4K
Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
1.4K
Analgesia and Pain Management01:25

Analgesia and Pain Management

1.7K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
1.7K
Primary Motives: Sleep, Sex, and Pain Avoidance01:24

Primary Motives: Sleep, Sex, and Pain Avoidance

5.7K
Primary motives such as sleep, sex, and pain avoidance are crucial drivers of behavior in humans and animals. These motives ensure survival, reproductive success, and overall well-being by prompting actions that meet essential bodily needs.
Sleep is a fundamental physiological drive that fosters a state of restfulness crucial for several bodily functions. It facilitates body restoration, the process by which the body repairs, rejuvenates, and maintains itself during sleep, including memory...
5.7K
Biodiversity and Human Values01:24

Biodiversity and Human Values

17.1K
Human civilization relies on biodiversity in many ways. Sudden changes in species biodiversity result in environmental changes that can modify weather patterns and therefore human civilizations.
17.1K
What is a Sensory System?01:31

What is a Sensory System?

101.1K
Sensory systems detect stimuli—such as light and sound waves—and transduce them into neural signals that can be interpreted by the nervous system. In addition to external stimuli detected by the senses, some sensory systems detect internal stimuli—such as the proprioceptors in muscles and tendons that send feedback about limb position.
101.1K
Data Reporting and Recording01:24

Data Reporting and Recording

5.5K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

New and developing anesthesia drugs.

Expert opinion on pharmacotherapy·2017
Same author

Diagnosis and management of neuropathic pain.

Pain management·2014
See all related articles

Related Experiment Video

Updated: Feb 5, 2026

The Sciatic Nerve Cuffing Model of Neuropathic Pain in Mice
07:09

The Sciatic Nerve Cuffing Model of Neuropathic Pain in Mice

Published on: July 16, 2014

49.4K

Fibromyalgia: is it a neuropathic pain?

Christina Wh Cheng1, Clara Sm Wong1, Grace Km Hui1

  • 1Department of Anaesthesiology, Queen Elizabeth Hospital, Hong Kong.

Pain Management
|September 14, 2018
PubMed
Summary

Fibromyalgia, a chronic pain condition, is increasingly linked to small fiber neuropathy. This finding challenges current diagnostic criteria and may alter future fibromyalgia management strategies.

More Related Videos

Chronic Constriction Injury of the Rat's Infraorbital Nerve IoN-CCI to Study Trigeminal Neuropathic Pain
10:52

Chronic Constriction Injury of the Rat's Infraorbital Nerve IoN-CCI to Study Trigeminal Neuropathic Pain

Published on: September 21, 2015

20.8K
Partial Sciatic Nerve Ligation: A Mouse Model of Chronic Neuropathic Pain to Study the Antinociceptive Effect of Novel Therapies
08:16

Partial Sciatic Nerve Ligation: A Mouse Model of Chronic Neuropathic Pain to Study the Antinociceptive Effect of Novel Therapies

Published on: October 6, 2022

7.9K

Related Experiment Videos

Last Updated: Feb 5, 2026

The Sciatic Nerve Cuffing Model of Neuropathic Pain in Mice
07:09

The Sciatic Nerve Cuffing Model of Neuropathic Pain in Mice

Published on: July 16, 2014

49.4K
Chronic Constriction Injury of the Rat's Infraorbital Nerve IoN-CCI to Study Trigeminal Neuropathic Pain
10:52

Chronic Constriction Injury of the Rat's Infraorbital Nerve IoN-CCI to Study Trigeminal Neuropathic Pain

Published on: September 21, 2015

20.8K
Partial Sciatic Nerve Ligation: A Mouse Model of Chronic Neuropathic Pain to Study the Antinociceptive Effect of Novel Therapies
08:16

Partial Sciatic Nerve Ligation: A Mouse Model of Chronic Neuropathic Pain to Study the Antinociceptive Effect of Novel Therapies

Published on: October 6, 2022

7.9K

Area of Science:

  • Neurology
  • Pain Medicine
  • Immunology

Background:

  • Fibromyalgia is a chronic pain syndrome with poorly understood causes.
  • Current understanding suggests central nervous system (CNS) dysfunction, but lacks definitive structural evidence.
  • Fibromyalgia has been excluded from neuropathic pain diagnoses since 2011.

Purpose of the Study:

  • To explore emerging evidence linking fibromyalgia pathophysiology to small fiber neuropathy.
  • To assess the potential impact of new findings on current diagnostic and management paradigms for fibromyalgia.

Main Methods:

  • Review of recent scientific literature and studies.
  • Analysis of diagnostic criteria evolution for neuropathic pain and fibromyalgia.
  • Examination of emerging pathophysiological evidence, including small fiber neuropathy.

Main Results:

  • Recent studies indicate small fiber neuropathy in fibromyalgia patients.
  • This evidence challenges the established exclusion of fibromyalgia from neuropathic pain categories.
  • The findings suggest a potential shift in understanding fibromyalgia's underlying mechanisms.

Conclusions:

  • Emerging evidence of small fiber neuropathy may necessitate a re-evaluation of fibromyalgia's pathophysiology.
  • This could lead to revised diagnostic approaches and therapeutic strategies for fibromyalgia.
  • Further research is crucial to confirm these findings and their clinical implications.