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Recurrent schilder's disease.

Anastasie M Dunn-Pirio1, Christopher Eckstein1

  • 1Department of Neurology, Duke University School of Medicine, 112 Baker House, Durham, NC 27710, United States.

Multiple Sclerosis and Related Disorders
|September 14, 2018
PubMed
Summary
This summary is machine-generated.

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Schilder's disease, a rare central nervous system disorder, usually presents once. This case shows a teenager experiencing a recurrence nearly a year after initial corticosteroid treatment.

Area of Science:

  • Neurology
  • Neuroimmunology
  • Demyelinating Diseases

Background:

  • Schilder's disease is a rare, aggressive central nervous system demyelinating disorder.
  • It is typically characterized by a monophasic course and responsiveness to steroid treatment.

Observation:

  • This report details an unusual case of a teenage patient diagnosed with Schilder's disease.
  • The patient received standard corticosteroid treatment following initial diagnosis.

Findings:

  • The patient experienced a clinical and radiographic recurrence of Schilder's disease.
  • This recurrence occurred approximately one year after the initial presentation and treatment.

Implications:

  • This case suggests that Schilder's disease can exhibit atypical, relapsing-remitting patterns.
Keywords:
Myelinoclastic diffuse sclerosisRituxumabSchilder's diseaseTumefactive multiple sclerosis

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  • Further research is needed to understand the long-term prognosis and optimal management strategies for recurrent Schilder's disease.