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Herbal medicine (Gancao Xiexin decoction) for Behcet disease: A systematic review protocol

Dongjie Wu1, Weiwei Lin, Ka-Wang Wong

  • 1School of Chinese Medicine, Hong Kong Baptist University, Hong Kong Graduate School, Zhejiang Chinese Medical University, Hangzhou The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang Province Department of Chemistry, Hong Kong Baptist University, Hong Kong SAR, China.

Medicine
|September 15, 2018
PubMed

Insights

Gancao Xiexin Decoction (GCXX) is being reviewed for Behcet disease (BD) treatment safety and efficacy. This systematic review synthesizes evidence on GCXX as a potential intervention for this refractory condition.

Area of Science:

  • Systematic review and meta-analysis.
  • Evidence-based medicine.

Background:

  • Behcet disease (BD) is a systemic vasculitis with no known cure.
  • Inflammation of blood vessels characterizes BD.
  • Refractory cases of BD pose a clinical challenge.

Purpose of the Study:

  • To evaluate the safety and efficacy of Gancao Xiexin Decoction (GCXX) for Behcet disease.
  • To provide a clinical reference for treating refractory BD.
  • To assess GCXX as a potential intervention for BD.

Main Methods:

  • Comprehensive literature search across multiple databases (PubMed, CENTRAL, EMBASE, AMED, CNKI, Wanfang, VIP).
  • Quality assessment of retrieved studies using Cochrane's handbook.
  • Data extraction and synthesis using Review Manager (RevMan) software V5.3.5.

Main Results:

  • This systematic review will synthesize high-quality evidence on Gancao Xiexin Decoction for Behcet disease.
  • The study aims to provide a robust analysis of existing research.

Conclusions:

  • The systematic review will provide evidence regarding the effectiveness of Gancao Xiexin Decoction for Behcet disease.
  • Evidence will be presented to support its use, particularly in menopausal women.
Abstract

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