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Maternal anaphylactic shock in pregnancy: A case report
Hye Ji Jeon1, Aeli Ryu, Jiwon Min
1Departments of Obstetrics and Gynaecology Anesthesiology and Pain Medicine, Soonchunhyang University College of Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.
Medicine
|September 15, 2018
Summary
Severe anaphylaxis during pregnancy is rare but dangerous. This case highlights a life-threatening reaction to cefotetan, a common antibiotic, necessitating emergency cesarean delivery for a positive maternal and infant outcome.
Area of Science:
- Obstetrics and Gynecology
- Allergy and Immunology
- Pharmacology
Background:
- Anaphylaxis in pregnancy is a rare but serious condition, potentially causing maternal hypotension and fetal hypoxia.
- Cesarean delivery rates are elevated in pregnant women experiencing anaphylaxis.
Observation:
- A pregnant patient developed anaphylaxis after a prophylactic antibiotic (cefotetan) skin test prior to cesarean delivery.
- Symptoms included rash, chest tightness, dyspnea, maternal hypotension, hypoxia, and fetal bradycardia.
Findings:
- Prompt management with epinephrine, glucocorticoids, and antihistamines was initiated for maternal anaphylaxis.
- An emergency cesarean section was performed, resulting in favorable maternal and fetal outcomes.
Implications:
- This is the first reported case of anaphylaxis to cefotetan during pregnancy.
- Antibiotic skin testing can trigger severe anaphylactic reactions, even in pregnant individuals.
- Early recognition and management are crucial for positive outcomes in pregnancy-related anaphylaxis.
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