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Published on: April 3, 2021
Multidisciplinary Perioperative Care for Children with Neuromuscular Disorders
J Matthew Kynes1, Martin Blakely2, Kevin Furman3
1Monroe Carell, Jr Children's Hospital at Vanderbilt, Nashville, TN 37232, USA. j.matt.kynes@vumc.org.
Insights
Children with neuromuscular diseases require specialized multidisciplinary perioperative care. This review outlines key considerations for safe anesthesia and surgical management in these vulnerable pediatric patients.
Area of Science:
- Pediatric Anesthesiology
- Neuromuscular Diseases
Background:
- Children with neuromuscular diseases (NMDs) present unique challenges for perioperative care.
- These conditions necessitate multidisciplinary collaboration among various specialists.
- Specific NMDs, like mitochondrial disease and muscular dystrophies, carry significant anesthetic risks, especially in undiagnosed cases.
Purpose of the Study:
- To provide an overview of critical considerations for perioperative management of pediatric patients with NMDs.
- To recommend a framework for optimizing care throughout the perioperative period.
- To highlight anesthetic implications and potential complications associated with NMDs.
Main Methods:
- Review of inherited neuromuscular conditions.
- Analysis of generalized perioperative concerns.
- Identification of specific anesthesia-related complications.
Main Results:
- Children with NMDs require comprehensive preoperative evaluation and optimization.
- Intraoperative management strategies must address the specific risks posed by NMDs.
- Postoperative care should focus on safely returning patients to their baseline status.
Conclusions:
- A structured, multidisciplinary approach is essential for safe perioperative care in pediatric NMD patients.
- Understanding specific pharmacologic implications of NMDs is crucial for anesthesia providers.
- Early identification and management of risks can improve outcomes for this vulnerable population.
Abstract:
Children with neuromuscular diseases present unique challenges to providing safe and appropriate perioperative care. Given the spectrum of disease etiologies and manifestations, this is a population that often requires specialized multidisciplinary care from pediatricians, geneticists, neurologists, dieticians, and pulmonologists which must also be coordinated with surgeons and anesthesiologists when these patients present for surgery. Several of these diseases also have specific pharmacologic implications for anesthesia, most notably mitochondrial disease and muscular dystrophies, which put them at additional risk during the perioperative period particularly in patients presenting without a formal diagnosis. Techniques and strategies to fully evaluate and optimize these patients preoperatively, manage them safely intraoperatively, and return them to their baseline status postoperative are particularly important in this vulnerable group of patients. Utilizing a review of inherited neuromuscular conditions, generalized perioperative concerns, and specific complications related to anesthesia, this article provides an overview of pertinent considerations and recommends a framework for management of these patients.
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