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Characteristics of breath sound in infants with risk factors for asthma development

Hiromi Shioya1, Hiromi Tadaki2, Fusae Yamazaki3

  • 1Division of Pediatrics, National Hospital Organization Yokohama Medical Center, Kanagawa, Japan.

Allergology International : Official Journal of the Japanese Society of Allergology
|September 15, 2018
PubMed

Insights

Breath sound analysis in infants with asthma risk factors revealed distinct patterns. Increased parameters like RPF75 and Slope in infants with allergies suggest potential for early asthma detection.

Area of Science:

  • Pediatric Pulmonology
  • Biomarkers
  • Respiratory Health

Background:

  • Breath sound parameters are explored as potential biomarkers for airway narrowing in children.
  • Investigating airway condition in infants with asthma risk factors is crucial for early detection.

Purpose of the Study:

  • To investigate breath sound characteristics in infants with risk factors for asthma development.
  • To assess the utility of breath sound analysis for early asthma detection in infants.

Main Methods:

  • Analyzed breath sound parameters including F99, Slope, A3/AT, RPF75, and RPF50 in 443 infants (3-24 months).
  • Utilized an ATS-DLD based Japanese questionnaire to examine infant airway conditions.
  • Included 283 healthy infants in the final analysis.

Main Results:

  • Significant increases in RPF75, RPF50, Slope, and F99 were observed in infants with positive allergy and atopic dermatitis results.
  • These findings indicate distinct breath sound profiles associated with allergic conditions in infants.

Conclusions:

  • Breath sound analysis demonstrates unique characteristics in infants predisposed to asthma.
  • This non-invasive method shows promise for assessing infant airways and aiding in early asthma development diagnosis.
Abstract

Keywords:
AsthmaBreath sound analysisInfantRisk factorsSound spectrum

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