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Updated: Feb 5, 2026

Murine Renal Transplantation Procedure
Published on: July 10, 2009
Two transplant renal arteries: One important lesson
Abhilash Koratala1, Alejandra Mena Gutierrez1, Gajapathiraju Chamarthi1
1Division of Nephrology, Hypertension and Renal Transplantation University of Florida Gainesville Florida.
Ischemic nephropathy in kidney transplant patients with acute kidney injury may be reversible. Carbon dioxide (CO2) angiography offers a safe alternative for vascular assessment in patients with impaired renal function, avoiding iodinated contrast.
Area of Science:
- Nephrology
- Transplant Surgery
- Vascular Imaging
Background:
- Ischemic nephropathy is a potential cause of graft dysfunction in renal transplant recipients.
- Acute kidney injury (AKI) in this population necessitates a high index of suspicion for reversible causes.
- Iodinated contrast agents pose risks for patients with renal dysfunction.
Purpose of the Study:
- To highlight the importance of considering ischemic nephropathy in renal transplant recipients with unexplained AKI.
- To evaluate the utility of carbon dioxide (CO2) angiography as an alternative imaging modality.
Main Methods:
- Case review of renal transplant recipients presenting with unexplained AKI.
- Utilized CO2 angiography to assess renal vasculature in patients with contraindications to iodinated contrast.
Main Results:
- Ischemic nephropathy was identified as a potentially reversible cause of AKI.
- CO2 angiography proved effective in evaluating the vasculature in patients with renal dysfunction.
Conclusions:
- Early suspicion and diagnosis of ischemic nephropathy are crucial for potential graft salvage.
- CO2 angiography is a viable and safe alternative for vascular assessment in renal transplant recipients with impaired renal function.
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