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Related Experiment Video

Updated: Feb 5, 2026

A Practical Guide to Phylogenetics for Nonexperts

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

Detection and Phylogenetic Characterization of

Yongshuai Peng^1,2, Kunlun Wang^1,2, Shanshan Zhao^1,2

¹College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.

Frontiers in Cellular and Infection Microbiology

|September 15, 2018

Summary

Anaplasma capra, a pathogen infecting ruminants and humans, was detected in 8.9% of sheep and goats across China. This study identified a novel variant, highlighting the zoonotic risk and wide distribution of this emerging disease.

Keywords:

Anaplasma Anaplasma capra gltA goat groEL msp4 sheep tick-borne diseases

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Published on: September 23, 2021

Area of Science:

Veterinary Microbiology
Zoonotic Diseases
Molecular Epidemiology

Background:

Anaplasma capra is an emerging zoonotic pathogen affecting ruminants and humans.
Understanding its prevalence and distribution in livestock is crucial for public health and animal health management.

Purpose of the Study:

To determine the occurrence and prevalence of Anaplasma capra in sheep and goats in China.
To identify genetic variants of A. capra and analyze their phylogenetic relationships.

Main Methods:

Nested PCR targeting the gltA gene.
Conventional PCR targeting the groEL and msp4 genes.
Phylogenetic analysis of detected Anaplasma sequences.

Main Results:

Anaplasma capra was detected in 8.9% (129/1453) of sheep and goat blood samples.
Prevalence was higher in goats (9.4%) than sheep (7.8%), with significant regional variations.
A novel A. capra variant (Variant II) was identified in Henan province, China.

Conclusions:

Sheep and goats in China are infected with Anaplasma capra, indicating its wide distribution.
The detection of a new variant underscores the need for ongoing surveillance.
Findings contribute to assessing public health risks associated with human anaplasmosis.