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Updated: Feb 5, 2026

Studying Brain Function in Children Using Magnetoencephalography
Published on: April 8, 2019
Current concepts and challenges in the radiologic assessment of brain tumors in children: part 2
Benita Tamrazi1, Kshitij Mankad2, Marvin Nelson3
1Department of Radiology, Children's Hospital Los Angeles, 4650 Sunset Blvd., MS #81, Los Angeles, CA, 90027, USA. btamrazi@chla.usc.edu.
Abstract:
Assessing tumor response is a large part of everyday clinical work in neuroradiology. However in the setting of tumor treatment, distinguishing tumor progression from treatment-related changes is difficult on conventional MRI sequences. This is made even more challenging in children where mainstay advanced imaging techniques that are often used to decipher progression versus treatment-related changes have technical limitations. In this review, we highlight the challenges in pediatric neuro-oncologic tumor assessment with discussion of pseudophenomenon including pseudoresponse and pseudoprogression. Additionally, we discuss the advanced imaging techniques often employed in neuroradiology to distinguish between pseudophenomenon and true progressive disease.
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