Associations between red reflex abnormality, consanguinity and intensive care hospitalization of newborns in Turkey

Zeynep Ozkurt1, Selahattin Balsak2, Yusuf Yildirim1

  • 1Department of Ophthalmology, Dicle University of Medicine, Diyarbakir, Turkey.

Insights

Red reflex screening in Southeast Turkey identified significant ocular abnormalities, particularly in newborns with consanguinity. Early detection through this vital eye test is crucial for preventing vision loss.

Area of Science:

  • Ophthalmology
  • Genetics
  • Neonatal Care

Background:

  • Red reflex screening is a critical, yet often overlooked, method for identifying serious infant eye conditions.
  • Early detection of ocular diseases can prevent vision impairment and address life-threatening issues.

Purpose of the Study:

  • To assess newborn red reflex abnormalities in Southeast Turkey.
  • To determine the prevalence of ocular diseases linked to abnormal red reflexes.
  • To investigate the association between consanguinity and red reflex abnormalities.

Main Methods:

  • Examined 1358 newborns using pencil light and direct ophthalmoscopy.
  • Categorized newborns into rooming-in units (RIU) and neonatal intensive care services (NICS).
  • Analyzed the correlation between consanguineous marriage and abnormal red reflexes.

Main Results:

  • Abnormal red reflexes were detected in 0.88% of RIU newborns and 2.51% of NICS newborns.
  • The sensitivity of pencil light examination for detecting abnormalities was 71.4%.
  • A significant association was found between consanguineous marriage and abnormal red reflexes (P = 0.017).

Conclusions:

  • Red reflex screening is essential for the early diagnosis of potentially blinding and life-threatening eye disorders in newborns.
  • The high prevalence of consanguinity in Southeast Turkey underscores the importance of this screening in the region.
  • Routine screening can facilitate timely intervention for pediatric eye conditions.
Abstract

Related Concept Videos

Hospitals-II00:59

Hospitals-II

Hospitals provide inpatient and outpatient services. Inpatient services provide care to patients that stay in the hospital for an extended period, ranging from days to months. Examples of inpatient services include intensive care units, hospital wards, or surgeries. Outpatient services provide care to patients who come to a hospital for a diagnostic or treatment but do not stay overnight —for example, diagnostic tests, surgical procedures, or health education.
Nurses that work in...
1.2K
Hospitals-I01:28

Hospitals-I

Hospitals offer medical and surgical care to the sick and injured, along with accommodation while they recover. At the same time, they also provide outpatient, emergency, psychiatric, and rehabilitation services to meet various community needs. In addition to providing medical care, hospitals also act as hubs for medical research and training. Hospitals use clinical procedures and evidence-based practice standards to deliver patient care. To deliver safe and efficient care, a nurse must stay up...
1.6K
Reflex Activity01:08

Reflex Activity

A reflex activity is an automatic, involuntary response to specific stimuli. It is a part of our survival mechanism, designed to protect us from potential harm. For example, when a bright light suddenly shines into our eyes, we instinctively close them or look away. This is a simple reflex activity orchestrated by the nervous system without conscious thought or effort.
A reflex exam is a diagnostic procedure performed by a healthcare professional to evaluate the functionality of a patient's...
3.3K
The Micturition Reflex01:26

The Micturition Reflex

Urination, or micturition involves the coordination of the bladder's detrusor muscle and two sphincters to ensure controlled bladder emptying.
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
2.8K
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
5.2K
Somatic Spinal Reflexes01:22

Somatic Spinal Reflexes

Somatic spinal reflexes are rapid, involuntary muscular responses to external stimuli that involve the somatic musculature and the spinal cord.
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...
5.3K