Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Standard Electrode Potentials03:02

Standard Electrode Potentials

50.4K
On comparing the reactivity of silver and lead, it is observed that the two ionic species, Ag+ (aq) and Pb2+ (aq), show a difference in their redox reactivity towards copper: the silver ion undergoes spontaneous reduction, while the lead ion does not. This relative redox activity can be easily quantified in electrochemical cells by a property called cell potential. This property is commonly known as cell voltage in electrochemistry, and it is a measure of the energy which accompanies the charge...
50.4K
Electrodes: Overview01:17

Electrodes: Overview

2.7K
 Electrochemical measurements are conducted in an electrochemical cell composed of various components that control and measure the current and potential. One fundamental component is electrodes, conductive materials that enable electron transfer reactions at their surfaces.
There are two main types of electrodes in electrochemical cells. The first type, known as the working or indicator electrode, has a potential that is sensitive to the analyte's concentration and reacts to changes in...
2.7K
Neural Regulation01:37

Neural Regulation

43.4K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
43.4K
Potentiometry: Types of Electrodes01:19

Potentiometry: Types of Electrodes

2.1K
Reference electrodes serve as a stable reference point for potentiometric measurements, while indicator and working electrodes react to variations in the composition of a solution.
The Standard Hydrogen Electrode (SHE) is a widely used reference electrode that maintains zero potential across all temperatures. However, its need for a continuous hydrogen gas supply renders it impractical for everyday use.
An alternative to SHE is the Saturated Calomel Electrode (SCE). This electrode features an...
2.1K
Potentiometry: Membrane Electrodes01:15

Potentiometry: Membrane Electrodes

1.8K
Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at...
1.8K
Neural Circuits01:25

Neural Circuits

2.8K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
2.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Editorial: Neuro-behavioral insights on low vision and beyond.

Frontiers in human neuroscience·2025
Same author

Wide-angle simulated artificial vision enhances spatial navigation and object interaction in a naturalistic environment.

Journal of neural engineering·2024
Same author

A Frequency-Switching Inductive Power Transfer System for Wireless, Miniaturised and Large-Scale Neural Interfaces.

IEEE transactions on biomedical circuits and systems·2024
Same author

An actor-model framework for visual sensory encoding.

Nature communications·2024
Same author

A Wearable Real-Time System for Simultaneous Wireless Power and Data Transmission to Cortical Visual Prosthesis.

IEEE transactions on biomedical circuits and systems·2024
Same author

Editorial: Neuromodulation and neural technologies for sight restoration.

Frontiers in cellular neuroscience·2023
Same journal

Ultra-flexible wireless endovascular stimulator for cortical simulation.

Journal of neural engineering·2026
Same journal

Influence of frequency and pulse train duration on respiratory responses during transcutaneous phrenic nerve stimulation in humans.

Journal of neural engineering·2026
Same journal

Dynamic functional graph-Laplacian priors integrated with optimization for EEG source localization.

Journal of neural engineering·2026
Same journal

Unveiling subject-specific causal latency in motor imagery: a physiologically transparent BCI via Riemannian tangent space fusion.

Journal of neural engineering·2026
Same journal

Cross-subject decoding of human neural data for speech Brain Computer Interfaces.

Journal of neural engineering·2026
Same journal

Cognitive and brain function enhancement in Gen X group after personalized, AI supervised EEG-neurofeedback training.

Journal of neural engineering·2026
See all related articles

Related Experiment Video

Updated: Feb 5, 2026

Surgical Implantation of Chronic Neural Electrodes for Recording Single Unit Activity and Electrocorticographic Signals
08:26

Surgical Implantation of Chronic Neural Electrodes for Recording Single Unit Activity and Electrocorticographic Signals

Published on: February 24, 2012

48.3K

Multilayer 3D electrodes for neural implants.

Marta Jole Ildelfonsa Airaghi Leccardi1, Paola Vagni1, Diego Ghezzi1

  • 1Medtronic Chair in Neuroengineering, Center for Neuroprosthetics and Institute of Bioengineering, School of Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Journal of Neural Engineering
|September 15, 2018
PubMed
Summary
This summary is machine-generated.

We developed a novel multilayer, three-dimensional (3D) electrode array for neural implants. This 3D electrode design enhances neural recording efficiency and allows for higher electrode density in a smaller probe size.

More Related Videos

Construction of a Multilayered Mesenchymal Stem Cell Sheet with a 3D Dynamic Culture System
07:44

Construction of a Multilayered Mesenchymal Stem Cell Sheet with a 3D Dynamic Culture System

Published on: October 20, 2018

7.9K
Chronic Implantation of Multiple Flexible Polymer Electrode Arrays
08:54

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Published on: October 4, 2019

11.4K

Related Experiment Videos

Last Updated: Feb 5, 2026

Surgical Implantation of Chronic Neural Electrodes for Recording Single Unit Activity and Electrocorticographic Signals
08:26

Surgical Implantation of Chronic Neural Electrodes for Recording Single Unit Activity and Electrocorticographic Signals

Published on: February 24, 2012

48.3K
Construction of a Multilayered Mesenchymal Stem Cell Sheet with a 3D Dynamic Culture System
07:44

Construction of a Multilayered Mesenchymal Stem Cell Sheet with a 3D Dynamic Culture System

Published on: October 20, 2018

7.9K
Chronic Implantation of Multiple Flexible Polymer Electrode Arrays
08:54

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Published on: October 4, 2019

11.4K

Area of Science:

  • Neuroscience
  • Materials Science
  • Bioengineering

Background:

  • High-density multielectrode arrays are crucial for neural implants to record and stimulate nervous system activity.
  • Current electrode arrays face limitations in electrode density and size preservation for precise neural interfacing.

Purpose of the Study:

  • To introduce a novel multilayer, three-dimensional (3D) electrode array and its manufacturing method.
  • To enhance electrode density and improve signal transduction efficiency for neural recording and stimulation.

Main Methods:

  • Fabrication of a multilayer, 3D electrode array with interconnects within a flexible substrate.
  • Characterization of recording capabilities using visually evoked cortical potentials in mice.
  • In vivo imaging of electrode integrity within clarified mouse brains using light-sheet microscopy.

Main Results:

  • The 3D electrode array achieves higher electrode density and reduced probe size.
  • Increased electrode surface area leads to lower electrochemical impedance and higher charge storage capacity.
  • Improved signal-to-noise ratio in neural recordings compared to flat electrodes.

Conclusions:

  • The multilayer 3D electrodes offer a viable technology for neural implants.
  • This technology ensures tissue proximity, higher recording/stimulating efficiencies, and reduced probe size.
  • The 3D electrode design facilitates higher electrode density for advanced neural interfacing.