Related Experiment Video
Updated: Feb 5, 2026

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
Published on: November 8, 2012
Relationship between extraversion personality and gray matter volume and functional connectivity density in healthy
Liwei Zou1, Lianzi Su1, Rongmiao Qi1
1Department of Radiology, the Second Hospital of Anhui Medical University, Hefei, Anhui province, China.
Abstract:
Extraversion and neuroticism are two main dimensions of Eysenck's personality. We assessed the relationship between extraversion and neuroticism with brain structure and function by voxel-based morphometry (VBM) and functional connectivity density (FCD). The resting state functional magnetic resonance image and high resolution structural T1 weighted images of 100 young healthy subjects were used in analysis. Our results showed that extraversion was negatively correlated with gray matter volume (GMV) of the bilateral putamen, and it was negatively correlated with FCD in the precuneus. No associations between neuroticism and brain structure and function changes. Overall, our results suggested that several brain regions involved in shaping of extraversion traits among young individuals, which may provide a neurobiological basis of extraversion.
Related Concept Videos
Applications of the Ideal Gas Law: Molar Mass, Density, and Volume
Relationship Formation
Functions of Connective Tissues
Hard connective tissues, such as bones and cartilage, provide structure and support to the body.
Relationship with Other Adult Family Members and Siblings
Classifying Matter by State
Physical and Chemical Properties of Matter

