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Updated: Feb 5, 2026

Rescue and Characterization of Recombinant Virus from a New World Zika Virus Infectious Clone
Published on: June 7, 2017
Zika Virus Vaccines: Challenges and Perspectives
Raquel das Neves Almeida1, Trina Racine2,3, Kelly G Magalhães4
1Laboratory of Immunology and Inflammation, University of Brasilia, Brasilia 70910-900, Brazil. raquel.das-neves-almeida.1@ulaval.ca.
Abstract:
Zika virus is an arbovirus that has rapidly spread within the Americas since 2014, presenting a variety of clinical manifestations and neurological complications resulting in congenital malformation, microcephaly, and possibly, in male infertility. These significant clinical manifestations have led investigators to develop several candidate vaccines specific to Zika virus. In this review we describe relevant targets for the development of vaccines specific for Zika virus, the development status of various vaccine candidates and their different platforms, as well as their clinical progression.
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